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Does vaginal bacterial colonization contribute to preterm birth in women with asymptomatic shortened cervix?
Steetskamp, J; Zander, M; Laufs, V; Elger, T; Hasenburg, A; Skala, C.
Afiliación
  • Steetskamp J; Department of Obstetrics and Gynecology, Mainz University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Zander M; . Josefs-Hospital Wiesbaden, Beethovenstraße 20, 65189, Wiesbaden, Germany.
  • Laufs V; Department of Obstetrics and Gynecology, Mainz University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Elger T; Department of Obstetrics and Gynecology, Mainz University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Hasenburg A; Department of Obstetrics and Gynecology, Mainz University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany.
  • Skala C; Department of Obstetrics and Gynecology, Mainz University Medical Center, Langenbeckstr. 1, 55131, Mainz, Germany. skala@uni-mainz.de.
Arch Gynecol Obstet ; 310(1): 121-127, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38578544
ABSTRACT

PURPOSE:

The aim of this study is to describe the typical microbial spectrum and the influence of distinct vaginal infections on preterm birth in pregnancies affected by cervical incompetence.

METHODS:

327 patients were admitted because of asymptomatic shortening of the cervix in the second and third trimester of pregnancy. Clinical data such as age, cervical length, gestational age at admission and at delivery and vaginal microbiologic findings were collected and analyzed.

RESULTS:

The spectrum of germs in the vagina revealed seven different distinct species; the most common bacteria were Ureaplasma spp. and E. coli. In 327 included patients, 217 revealed a bacterial colonization, 110 did not. Most common bacteria in women with preterm birth before 34 weeks were Ureaplasma spp., while E. coli was most common in women undergoing preterm birth after 34 weeks. Nevertheless, the rates of occurrence of these bacterial taxa were not significantly different between who underwent preterm birth to those who did not.

CONCLUSIONS:

This study gives an overview over the vaginal bacterial colonization in pregnant women with cervical incompetence. The clinical relevance of vaginal bacterial colonization remains unclear.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vagina / Cuello del Útero / Nacimiento Prematuro Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Arch Gynecol Obstet Asunto de la revista: GINECOLOGIA / OBSTETRICIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vagina / Cuello del Útero / Nacimiento Prematuro Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Arch Gynecol Obstet Asunto de la revista: GINECOLOGIA / OBSTETRICIA Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania