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Flow Diverter Combined with Coil Embolization for Acutely Ruptured Intracranial Aneurysms: A Single Center Experience.
Liu, Jie; Zhou, Liyun; Ling, Yuhui; Xiang, Xiuzhi; Wang, Peiming.
Afiliación
  • Liu J; Department of Neurointervention, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
  • Zhou L; Department of Neurointervention, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
  • Ling Y; Department of Neurointervention, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
  • Xiang X; Department of Neurointervention, Guangdong Sanjiu Brain Hospital, Guangzhou, China.
  • Wang P; Department of Neurointervention, Guangdong Sanjiu Brain Hospital, Guangzhou, China. Electronic address: wang_pm_39@sina.com.
World Neurosurg ; 186: e449-e455, 2024 06.
Article en En | MEDLINE | ID: mdl-38575061
ABSTRACT

BACKGROUND:

Extensive research has confirmed the safety and effectiveness of flow diverters in the treatment of unruptured intracranial aneurysms. However, their use in cases of acute rupture remains a subject of debate.

METHODS:

This study was conducted as a single-center retrospective investigation from January 2018 to January 2022 and included patients with acutely ruptured intracranial aneurysms (within three days of rupture) who were treated using the Pipeline Embolization Device with adjunctive coil embolization. Patient demographics, operative procedures, and outcomes were analyzed. Antiplatelet therapy included intra-arterial tirofiban and postoperative dual therapy with clopidogrel and aspirin.

RESULTS:

A total of 21 patients (5 males, 16 females) diagnosed with acutely ruptured intracranial aneurysms were included in this study. The aneurysm types included 7 blood blister-like aneurysms (30.0%), 3 dissecting (14.3%), and 1 fusiform aneurysm (4.8%). Perioperative complications occurred in 2 patients (9.5%), and both cases involved thrombogenesis. Nineteen patients completed digital subtraction angiography during follow-up, with an average follow-up time of 8.7 months (5 - 18 months). Results showed a complete embolization rate of 94.7% (18/19), with a partial aneurysm still present in 1 patient. A total of 90.4% (19/21) of patients had a favorable prognosis (modified Rankin Scale score = 0 - 2).

CONCLUSIONS:

The Pipeline Embolization Device with adjunctive coil embolization proved to be a viable option for managing acutely ruptured intracranial aneurysms, notwithstanding the potential for ischemic complications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma Intracraneal / Aneurisma Roto / Embolización Terapéutica Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma Intracraneal / Aneurisma Roto / Embolización Terapéutica Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: World Neurosurg Asunto de la revista: NEUROCIRURGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos