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Huge mesenchymal hamartoma in a young adult: a case report.
Pinelli, Domenico; Guerci, Claudio; Cammarata, Francesco; Cirelli, Riccardo; Scatigno, Agnese; Colledan, Michele.
Afiliación
  • Pinelli D; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital, Bergamo 24127, Italy.
  • Guerci C; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital, Bergamo 24127, Italy.
  • Cammarata F; University of Milan, Via Festa del Perdono 7, Milano 20122, Italy.
  • Cirelli R; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital, Bergamo 24127, Italy.
  • Scatigno A; University of Milan, Via Festa del Perdono 7, Milano 20122, Italy.
  • Colledan M; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital, Bergamo 24127, Italy.
J Surg Case Rep ; 2024(4): rjae184, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38572276
ABSTRACT
Mesenchymal hamartoma of the liver (MHL) is rare. Less than 50 adult cases have been described. Due to their potential degeneration or recurrence, a complete surgical resection must be performed. We describe a case of a 26-year-old with a palpable solid lesion, which displaced abdominal organs. Percutaneous needle biopsies suggested the diagnosis of MHL. A right hemi-hepatectomy without segment 1 was performed; the post-operative course was uneventful. The mesenchymal component of the tumour was reactive to desmin and smooth muscle actin. Low proliferation index was confirmed (MIB1). Genetic counselling the sequencing analysis of DICER1 and CDKN1C gene was negative, DNA methylation analysis on the chromosome 11p15 region was normal. After 42 months, there was no recurrence. In conclusion, clinicians should consider MHL in the differential diagnosis. The dimension and the need of radicality impose major liver resections or liver transplantations, which should be performed in referral centres.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Surg Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Surg Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido