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Use of antidepressants in the treatment of chronic orofacial pain caused by temporomandibular disorders: A randomized controlled clinical trial.
de Sousa, Bruno Macedo; López-Valverde, Antonio; Caramelo, Francisco; Rodrigues, Maria Joao; López-Valverde, Nansi.
Afiliación
  • de Sousa BM; Institute for Occlusion and Orofacial Pain Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • López-Valverde A; Department of Surgery, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.
  • Caramelo F; Laboratory of Biostatistics and Medical Informatics, Coimbra, Institute for Clinical and Biomedical Research (iCBR), School of Medicine, University of Coimbra, Coimbra, Portugal.
  • Rodrigues MJ; Institute for Occlusion and Orofacial Pain Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
  • López-Valverde N; Department of Surgery, University of Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain. Electronic address: nlovalher@usal.es.
Med Clin (Barc) ; 163(2): 74-77, 2024 07 26.
Article en En, Es | MEDLINE | ID: mdl-38570297
ABSTRACT
BACKGROUND AND

OBJECTIVE:

Temporomandibular disorders (TMDs) are a common pathology, associated with pain in the facial territory and with associated psychological disorders, such as anxiety and depression. The aim of this study was to evaluate the efficacy of antidepressants in the treatment of pain associated with TMD. MATERIALS AND

METHODS:

Sixty four patients suffering from chronic orofacial pain, randomly distributed in 3 groups control group treated with night splint, group treated with 10mg/day of citalopram and group treated with 25mg/day of amitriptyline. Pain intensity was assessed, randomly, by a single blinded evaluator, according to the VAS at baseline and after one, three, six and nine weeks.

RESULTS:

All groups showed a reduction of pain throughout the period of time evaluated, however, the group treated with amitriptyline showed the best pain reduction results 3.3±1.5, 1.5±1.4 and 0.9±1.3 at 3, 6 and 9 weeks, respectively.

CONCLUSIONS:

Low doses of amitriptyline appear to be a good therapeutic option in patients with TMDs suffering from chronic orofacial pain.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Facial / Citalopram / Trastornos de la Articulación Temporomandibular / Dolor Crónico / Amitriptilina Límite: Adult / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: España
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Facial / Citalopram / Trastornos de la Articulación Temporomandibular / Dolor Crónico / Amitriptilina Límite: Adult / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: España