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Aortopathy and aortic valve surgery in patients with bicuspid aortic valve with and without raphe.
Bellino, Michele; Antonini-Canterin, Francesco; Bossone, Eduardo; Faggiano, Pompilio; Chirillo, Fabio; La Carrubba, Salvatore; Faganello, Giorgio; Cecconi, Moreno; Zito, Concetta; Dasseni, Nicolò; Nistri, Stefano; Moreo, Antonella; Fabiani, Iacopo; Faden, Giacomo; Agostini, Francesco; Manuppelli, Vincenzo; Cameli, Matteo; Cresti, Alberto; Dentamaro, Ilaria; Monte, Ines Paola; Barbieri, Andrea; Ciampi, Quirino; Giorgi, Mauro; Galasso, Gennaro; Carerj, Scipione; Pepi, Mauro; Benedetto, Frank; Colonna, Paolo; Citro, Rodolfo.
Afiliación
  • Bellino M; Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
  • Antonini-Canterin F; Rehabilitative Cardiology, Highly Specialized Rehabilitation Hospital, Motta di Livenza (TV), Italy.
  • Bossone E; Department of Public Health, "Federico II" University of Naples, Naples, Italy.
  • Faggiano P; Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Institute of Cardiology, ASST Spedali Civili di Brescia, Brescia, Italy.
  • Chirillo F; Department of Cardiology, Ospedale San Bassiano, Bassano del Grappa (VI), Italy.
  • La Carrubba S; Department of Internal Medicine, Villa Sofia, Cervello Hospital, Palermo, Italy.
  • Faganello G; Cardiovascular Department, University Hospital and Health Services of Trieste, Trieste, Italy.
  • Cecconi M; Department of Cardiology and Cardiac Surgery, Azienda Ospedaliero Universitaria, Ospedali Riuniti, Ancona, Italy.
  • Zito C; Section of Cardiology, Department of Clinical and Experimental Medicine, University of Messina, Azienda Ospedaliera Universitaria "Policlinico G. Martino", Messina, Italy.
  • Dasseni N; Cardiology Division, ASST Franciacorta, Chiari (BS), Italy.
  • Nistri S; Department of Cardiology, CMSR, Altavilla Vicentina (VI), Italy.
  • Moreo A; Cardiology IV, "A. De Gasperis" Department, ASST Niguarda Metropolitan Hospital, Milan, Italy.
  • Fabiani I; Division of Cardiology and Cardiovascular Medicine, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.
  • Faden G; Cardiology Division, Pieve di Coriano (BS), Italy.
  • Agostini F; Cardiology Division, Mantova Hospital, Mantova, Italy.
  • Manuppelli V; Department of Cardiology, University of Foggia, Foggia, Italy.
  • Cameli M; Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Cresti A; Cardiology, Cardio Neuro Vascular Department, Asl Sudest Toscana, Hospital of Grosseto, Grosseto, Italy.
  • Dentamaro I; Cardiology Department and Cardiovascular Imaging Laboratory, Hospital Miulli, Bari, Italy.
  • Monte IP; Department of General Surgery and Medical Surgery Specialties, University of Catania, AOU Policlinico G. Rodolico-San Marco, Catania, Italy.
  • Barbieri A; Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
  • Ciampi Q; Cardiology Division, Fatebenefratelli Hospital, Benevento, Italy.
  • Giorgi M; Department of Cardiology, University Hospital Città della Scienza e Salute, Molinette Hospital, Turin, Italy.
  • Galasso G; Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
  • Carerj S; Section of Cardiology, Department of Clinical and Experimental Medicine, University of Messina, Azienda Ospedaliera Universitaria "Policlinico G. Martino", Messina, Italy.
  • Pepi M; Department of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Benedetto F; Cardiology, G.O.M. "Bianchi Melacrino Morelli", Reggio Calabria, Italy.
  • Colonna P; Department of Cardiology, Hospital Policlinico of Bari, Bari, Italy.
  • Citro R; Cardio-Thoracic and Vascular Department, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy; Department of Vascular Physiopathology, IRCCS Neuromed, Pozzilli (IS), Italy. Electronic address: rodolfocitro@gmail.com.
Int J Cardiol ; 407: 132000, 2024 Jul 15.
Article en En | MEDLINE | ID: mdl-38561108
ABSTRACT

AIM:

To evaluate the association between raphe in bicuspid aortic valve (BAV) patients and valve dysfunction, aortopathy and aortic valve surgery in the REBECCA registry [REgistro della valvola aortica Bicuspide della Società Italiana di ECocardiografia e CArdiovascular Imaging (SIECVI)].

METHODS:

Prevalence of aortic valve dysfunction and aortopathy was investigated in BAV patients with and without raphe. Aortic valve dysfunction (regurgitation or stenosis) was categorized as mild, moderate and severe. Aortopathy was defined as annulus ≥14 mm/m2; root ≥20 mm/m2; sinotubular junction ≥16 mm/m2; ascending aorta ≥17 mm/m2, and classified in Type A, isolated ascending aorta dilatation; Type B, aortic root and ascending aorta dilatation; and Type C, isolated aortic root dilatation.

RESULTS:

Overall, 695 patients with BAV were enrolled; 520 (74.8%) with raphe and 175 (25.2%) without raphe. BAV patients with raphe presented more frequently with moderate or severe aortic stenosis than BAV patients without raphe (183 [35.2%] vs 34 [19.4%], p < 0.001). A higher prevalence of aortopathy, particularly Type B, was observed in patients with vs without raphe. At multivariable analysis, raphe was a predictor of aortic valve surgery at three-year follow-up (odds ratio 2.19, 95% confidence interval 1.08-4.44, p < 0.001).

CONCLUSIONS:

Patients with BAV and raphe have a higher prevalence of significant aortic stenosis, aortopathy, especially Type B, and a higher risk of undergoing aortic valve surgery at three-year follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Válvula Aórtica / Sistema de Registros / Enfermedad de la Válvula Aórtica Bicúspide / Enfermedades de las Válvulas Cardíacas Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Válvula Aórtica / Sistema de Registros / Enfermedad de la Válvula Aórtica Bicúspide / Enfermedades de las Válvulas Cardíacas Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Int J Cardiol Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos