Your browser doesn't support javascript.
loading
Effect of MSX1 on the cellular function of cardiomyocytes.
Linhuan, Huang; Liangying, Zhong; Shaobin, Lin; Caixia, Zhu; Danlei, Cai; Siqi, Huang; Peiming, Hong; Shu, Kong; Yingjun, Xie; Yanmin, Luo.
Afiliación
  • Linhuan H; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: hlhuan@mail.sysu.edu.cn.
  • Liangying Z; Department of Clinical Laboratory, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: zhongly6@mail.sysu.edu.cn.
  • Shaobin L; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: linshb7@mail.sysu.edu.cn.
  • Caixia Z; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: zhucx3@mailsysu.edu.cn.
  • Danlei C; Department of Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: caidanl@mail.sysu.edu.cn.
  • Siqi H; Department of Obstetrics and Gynecology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine, The Third Af
  • Peiming H; Department of Obstetrics and Gynecology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine, The Third Af
  • Shu K; Department of Obstetrics and Gynecology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine, The Third Af
  • Yingjun X; Department of Obstetrics and Gynecology, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine, The Third Af
  • Yanmin L; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510100, Guangdong Province, PR China. Electronic address: luoyanm@mail.sysu.edu.cn.
Gene ; 916: 148419, 2024 Jul 20.
Article en En | MEDLINE | ID: mdl-38556116
ABSTRACT
MSX1 (Muscle Segment Homeobox 1) has pleiotropic effects in various tissues, including cardiomyocytes, while the effect of MSX1 on cardiomyocyte cellular function was not well known. In this study, we used AC16 cell culture, real-time fluorescence quantitative PCR (qPCR), protein blotting (Western blot), flow cytometry apoptosis assay and lactate dehydrogenase (LDH) ELISA (Enzyme-Linked Immunosorbnent Assay) to investigate the effect of the MSX1 gene on cardiomyocyte function. The results showed that MSX1 plays a protective role against hypoxia of cardiomyocytes. However, further studies are required to fully understand the role of MSX1 in the regulation of LDH expression in different cell types and under different conditions.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / Miocitos Cardíacos / Factor de Transcripción MSX1 Límite: Animals / Humans Idioma: En Revista: Gene Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / Miocitos Cardíacos / Factor de Transcripción MSX1 Límite: Animals / Humans Idioma: En Revista: Gene Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos