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Measurement of cerebrospinal fluid lactate levels in pediatric patients with suspected ventriculoperitoneal shunt infection: A retrospective cohort study.
Fernandez V, Jose Pablo; Acosta G, Natalia; Flores S, Tamara; Fernández, Gabriela.
Afiliación
  • Fernandez V JP; Pediatrician, Chile; Pediatric Intensive Care Unit. Instituto de Neurocirugía Asenjo. Santiago, Chile. Electronic address: jose.pablo.fernandez@redsalud.gov.cl.
  • Acosta G N; Pediatrician, Chile; Pediatric Intensive Care Unit. Instituto de Neurocirugía Asenjo. Santiago, Chile.
  • Flores S T; Neurosurgeon, Chile; Pediatric Intensive Care Unit. Instituto de Neurocirugía Asenjo. Santiago, Chile.
  • Fernández G; Neurosurgery Resident, Universidad de Chile, Chile.
Clin Neurol Neurosurg ; 240: 108256, 2024 05.
Article en En | MEDLINE | ID: mdl-38547629
ABSTRACT

INTRODUCTION:

Ventriculoperitoneal shunt (VPS) infection is a severe complication. Early diagnosis could help to decrease morbidity and treatment costs. Lactate has been used for the diagnosis of other central nervous system infections. The aim of this study is to determine the usefulness of lactate for the diagnosis of VPS infection.

METHODOLOGY:

Retrospective cohort study. Lactate was measured in patients who consulted with VPS dysfunction between May 2019 and May 2022. Mean were compared according to culture results. A Receiver Operating Characteristic (ROC) curve was performed to determine the appropriate cut-off point.

RESULT:

Lactate has a high negative predictive value but a low positive predictive value for the diagnosis of ventriculitis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivación Ventriculoperitoneal / Ácido Láctico Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Clin Neurol Neurosurg Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivación Ventriculoperitoneal / Ácido Láctico Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Clin Neurol Neurosurg Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos