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Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes.
Schulte, Josh; Peterson, Kyle; Thomsen, Timothy; Lentz, Steven; Hall, Mederic; Slayman, Tyler.
Afiliación
  • Schulte J; UT Southwestern Medical Center, Dallas, Texas, USA.
  • Peterson K; University of Wisconsin, Madison, Wisconsin, USA.
  • Thomsen T; University of Iowa, Iowa City, Iowa, USA.
  • Lentz S; University of Iowa, Iowa City, Iowa, USA.
  • Hall M; University of Iowa, Iowa City, Iowa, USA.
  • Slayman T; University of Iowa, Iowa City, Iowa, USA.
PM R ; 16(4): 316-322, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38545733
ABSTRACT

OBJECTIVE:

To compare the effectiveness, compliance, and side effect profile between daily or three times weekly (TIW) oral iron supplementation regimens in treating iron deficiency nonanemia (IDNA) in National Collegiate Athletic Association (NCAA) Division 1 female track and field or soccer athletes.

DESIGN:

Prospective cohort study.

SETTING:

Division 1 collegiate athletics.

PARTICIPANTS:

Thirty-three NCAA Division 1 female athletes (18 track and field, 15 soccer).

INTERVENTIONS:

Daily or TIW dosing of ferrous bisglycinate. MAIN OUTCOME

MEASURES:

Serum ferritin (µg/L) was measured before and after 8 weeks of supplementation. Self-reported compliance and side effect profile was assessed by electronic survey every 2 weeks.

RESULTS:

The average main effect for the TIW regimen was a significant increase of 5.17 µg/L (95% CI 0.86-9.47) in serum ferritin (p = .02). The average main effect for the daily regimen was a significant increase of 12.88 µg/L (95% CI 4.84-20.93) in serum ferritin (p = .003). The estimated average effect of the treatment on the treated between regimens was a nonsignificant decrease of -7.17 µg/L (95% CI -19.02 - 3.59) in serum ferritin (p = .17). Thus, the TIW regimen increased serum ferritin 7.17 units less than the daily regimen on average after 8 weeks of supplementation. The athletes following the daily regimen experienced significantly more nausea (p = .04) and constipation (p = .002) compared to the TIW regimen. There was no statistical difference in compliance between the two groups (p = .14).

CONCLUSIONS:

Both the daily and TIW regimens increased serum ferritin. Compared to the daily regimen, the TIW regimen produced a smaller increase in serum ferritin but less nausea and constipation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deportes / Deficiencias de Hierro Límite: Female / Humans Idioma: En Revista: PM R Asunto de la revista: MEDICINA FISICA / REABILITACAO / TRAUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Deportes / Deficiencias de Hierro Límite: Female / Humans Idioma: En Revista: PM R Asunto de la revista: MEDICINA FISICA / REABILITACAO / TRAUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos