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The Role of Lurasidone in Managing Depressive Symptoms in People with Schizophrenia: A Review.
Fiorillo, Andrea; Sampogna, Gaia; Albert, Umberto; Bondi, Emi; De Giorgi, Serafino; Fagiolini, Andrea; Pompili, Maurizio; Serafini, Gianluca; Volpe, Umberto; Vita, Antonio.
Afiliación
  • Fiorillo A; Department of Psychiatry, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
  • Sampogna G; Department of Psychiatry, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
  • Albert U; Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
  • Bondi E; Department of Mental Health, Azienda Sanitaria Universitaria Giuliano Isontina-ASUGI, 34127 Trieste, Italy.
  • De Giorgi S; Department of Mental Health and Addictions, ASST Papa Giovanni XXIII, 24121 Bergamo, Italy.
  • Fagiolini A; Department of Mental Health, ASL Lecce, 73100 Lecce, Italy.
  • Pompili M; Division of Psychiatry, University of Siena, 53100 Siena, Italy.
  • Serafini G; Department of Neurosciences, Mental Health and Sensory Organs, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa, 1035, 00189 Rome, Italy.
  • Volpe U; Section of Psychiatry, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16131 Genoa, Italy.
  • Vita A; IRCCS Ospedale Policlinico San Martino, 16131 Genoa, Italy.
Brain Sci ; 14(3)2024 Feb 28.
Article en En | MEDLINE | ID: mdl-38539614
ABSTRACT

BACKGROUND:

Schizophrenia is a severe mental disorder characterized by positive, negative, affective, and cognitive symptoms. Affective symptoms in patients with schizophrenia have traditionally been overlooked or even neglected because they are not considered as fundamental as positive and negative symptoms in the choice of medication.

METHODS:

This paper aims to systematically evaluate the efficacy and safety of lurasidone in the treatment of depressive symptoms of schizophrenia.

RESULTS:

Lurasidone appears to be particularly effective on the depressive symptomatology of schizophrenia while also alleviating the positive and negative symptoms associated with the illness.

CONCLUSIONS:

The efficacy of lurasidone in treating patients with first-episode psychosis who present with predominant depressive symptoms suggests that this medication may be a valuable treatment option not only for established cases of schizophrenia but also for individuals in the early stages of the illness. The good tolerability of lurasidone is an important factor that may positively influence treatment decisions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Brain Sci Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza