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Morphology of the papilla can predict procedural safety and efficacy of ERCP-a systematic review and meta-analysis.
Tari, Edina; Gagyi, Endre Botond; Rancz, Anett; Veres, Dániel Sándor; Váncsa, Szilárd; Hegyi, Péter Jeno; Hagymási, Krisztina; Hegyi, Péter; Eross, Bálint.
Afiliación
  • Tari E; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Gagyi EB; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary.
  • Rancz A; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Veres DS; Selye János Doctoral College for Advanced Studies, Semmelweis University, Budapest, Hungary.
  • Váncsa S; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Hegyi PJ; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Hagymási K; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
  • Hegyi P; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Eross B; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary.
Sci Rep ; 14(1): 7341, 2024 Mar 28.
Article en En | MEDLINE | ID: mdl-38538734
ABSTRACT
Endoscopic Retrograde Cholangiopancreatography (ERCP) is the primary therapeutic procedure for pancreaticobiliary disorders, and studies highlighted the impact of papilla anatomy on its efficacy and safety. Our objective was to quantify the influence of papilla morphology on ERCP outcomes. We systematically searched three medical databases in September 2022, focusing on studies detailing the cannulation process or the rate of adverse events in the context of papilla morphology. The Haraldsson classification served as the primary system for papilla morphology, and a pooled event rate with a 95% confidence interval was calculated as the effect size measure. Out of 17 eligible studies, 14 were included in the quantitative synthesis. In studies using the Haraldsson classification, the rate of difficult cannulation was the lowest in type I papilla (26%), while the highest one was observed in the case of type IV papilla (41%). For post-ERCP pancreatitis, the event rate was the highest in type II papilla (11%) and the lowest in type I and III papilla (6-6%). No significant difference was observed in the cannulation failure and post-ERCP bleeding event rates between the papilla types. In conclusion, certain papilla morphologies are associated with a higher rate of difficult cannulation and post-ERCP pancreatitis.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ampolla Hepatopancreática / Colangiopancreatografia Retrógrada Endoscópica Límite: Humans Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ampolla Hepatopancreática / Colangiopancreatografia Retrógrada Endoscópica Límite: Humans Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: Hungria Pais de publicación: Reino Unido