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Association Between Defibrillation Using LIFEPAK 15 or ZOLL X Series and Survival Outcomes in Out-of-Hospital Cardiac Arrest: A Nationwide Cohort Study.
Meilandt, Carsten; Qvortrup, Mette; Bøtker, Morten Thingemann; Folke, Fredrik; Borup, Lars; Christensen, Helle Collatz; Milling, Louise; Lauridsen, Kasper G; Løfgren, Bo.
Afiliación
  • Meilandt C; Prehospital Emergency Medical Services, Central Denmark Region Aarhus Denmark.
  • Qvortrup M; Department of Research and Development Prehospital Emergency Medical Services, Central Denmark Region Aarhus Denmark.
  • Bøtker MT; Department of Cardiology Viborg Regional Hospital Viborg Denmark.
  • Folke F; Prehospital Emergency Medical Services, Central Denmark Region Aarhus Denmark.
  • Borup L; Department of Research and Development Prehospital Emergency Medical Services, Central Denmark Region Aarhus Denmark.
  • Christensen HC; Copenhagen Emergency Medical Services, Capital Region of Denmark Copenhagen Denmark.
  • Milling L; Department of Cardiology Herlev Gentofte University Hospital Herlev Denmark.
  • Lauridsen KG; Department of Clinical Medicine University of Copenhagen Copenhagen Denmark.
  • Løfgren B; Prehospital Emergency Medical Services, North Denmark Region Aalborg Denmark.
J Am Heart Assoc ; 13(7): e033913, 2024 Apr 02.
Article en En | MEDLINE | ID: mdl-38533945
ABSTRACT

BACKGROUND:

Defibrillation is essential for achieving return of spontaneous circulation (ROSC) following out-of-hospital cardiac arrest (OHCA) with shockable rhythms. This study aimed to investigate if the type of defibrillator used was associated with ROSC in OHCA. METHODS AND

RESULTS:

This study included adult patients with OHCA from the Danish Cardiac Arrest Registry from 2016 to 2021 with at least 1 defibrillation by the emergency medical services. We used multivariable logistic regression and a difference-in-difference analysis, including all patients with or without emergency medical services shock to assess the causal inference of using the different defibrillator models (LIFEPAK or ZOLL) for OHCA defibrillation. Among 6516 patients, 77% were male, the median age (quartile 1; quartile 3) was 70 (59; 79), and 57% achieved ROSC. In total, 5514 patients (85%) were defibrillated using LIFEPAK (ROSC 56%) and 1002 patients (15%) were defibrillated using ZOLL (ROSC 63%). Patients defibrillated using ZOLL had an increased adjusted odds ratio (aOR) for ROSC compared with LIFEPAK (aOR, 1.22 [95% CI, 1.04-1.43]). There was no significant difference in 30-day mortality (aOR, 1.11 [95% CI, 0.95-1.30]). Patients without emergency medical services defibrillation, but treated by ZOLL-equipped emergency medical services, had a nonsignificant aOR for ROSC compared with LIFEPAK (aOR, 1.10 [95% CI, 0.99-1.23]) and the difference-in-difference analysis was not statistically significant (OR, 1.10 [95% CI, 0.91-1.34]).

CONCLUSIONS:

Defibrillation using ZOLL X Series was associated with increased odds for ROSC compared with defibrillation using LIFEPAK 15 for patients with OHCA. However, a difference-in-difference analysis suggested that other factors may be responsible for the observed association.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reanimación Cardiopulmonar / Servicios Médicos de Urgencia / Paro Cardíaco Extrahospitalario Límite: Adult / Female / Humans / Male Idioma: En Revista: J Am Heart Assoc Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reanimación Cardiopulmonar / Servicios Médicos de Urgencia / Paro Cardíaco Extrahospitalario Límite: Adult / Female / Humans / Male Idioma: En Revista: J Am Heart Assoc Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido