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Cessation of Smoking Trial in the Emergency Department (COSTED): a multicentre randomised controlled trial.
Pope, Ian; Clark, Lucy V; Clark, Allan; Ward, Emma; Belderson, Pippa; Stirling, Susan; Parrott, Steve; Li, Jinshuo; Coats, Tim; Bauld, Linda; Holland, Richard; Gentry, Sarah; Agrawal, Sanjay; Bloom, Benjamin Michael; Boyle, Adrian A; Gray, Alasdair J; Morris, M Geraint; Livingstone-Banks, Jonathan; Notley, Caitlin.
Afiliación
  • Pope I; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK i.pope@uea.ac.uk.
  • Clark LV; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Clark A; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Ward E; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Belderson P; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Stirling S; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Parrott S; Department of Health Sciences, University of York, York, UK.
  • Li J; Department of Health Sciences, University of York, York, UK.
  • Coats T; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
  • Bauld L; Usher Institute, The University of Edinburgh, Edinburgh, UK.
  • Holland R; University of Exeter, Exeter, UK.
  • Gentry S; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
  • Agrawal S; Leicester Royal Infirmary, Leicester, UK.
  • Bloom BM; Emergency Department, Barts Health NHS Trust, London, UK.
  • Boyle AA; Emergency Department, Addenbrooke's Hospital, Cambridge, UK.
  • Gray AJ; Emergency Department, Royal Infirmary of Edinburgh, Edinburgh, Edinburgh, UK.
  • Morris MG; Emergency Department, Homerton University Hospital NHS Foundation Trust, London, UK.
  • Livingstone-Banks J; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Notley C; Norwich Medical School, University of East Anglia Norwich Medical School, Norwich, UK.
Emerg Med J ; 41(5): 276-282, 2024 Apr 22.
Article en En | MEDLINE | ID: mdl-38531658
ABSTRACT

BACKGROUND:

Supporting people to quit smoking is one of the most powerful interventions to improve health. The Emergency Department (ED) represents a potentially valuable opportunity to deliver a smoking cessation intervention if it is sufficiently resourced. The objective of this trial was to determine whether an opportunistic ED-based smoking cessation intervention can help people to quit smoking.

METHODS:

In this multicentre, parallel-group, randomised controlled superiority trial conducted between January and August 2022, adults who smoked daily and attended one of six UK EDs were randomised to intervention (brief advice, e-cigarette starter kit and referral to stop smoking services) or control (written information on stop smoking services). The primary outcome was biochemically validated abstinence at 6 months.

RESULTS:

An intention-to-treat analysis included 972 of 1443 people screened for inclusion (484 in the intervention group, 488 in the control group). Of 975 participants randomised, 3 were subsequently excluded, 17 withdrew and 287 were lost to follow-up. The 6-month biochemically-verified abstinence rate was 7.2% in the intervention group and 4.1% in the control group (relative risk 1.76; 95% CI 1.03 to 3.01; p=0.038). Self-reported 7-day abstinence at 6 months was 23.3% in the intervention group and 12.9% in the control group (relative risk 1.80; 95% CI 1.36 to 2.38; p<0.001). No serious adverse events related to taking part in the trial were reported.

CONCLUSIONS:

An opportunistic smoking cessation intervention comprising brief advice, an e-cigarette starter kit and referral to stop smoking services is effective for sustained smoking abstinence with few reported adverse events. TRIAL REGISTRATION NUMBER NCT04854616.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Emerg Med J Asunto de la revista: MEDICINA DE EMERGENCIA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Emerg Med J Asunto de la revista: MEDICINA DE EMERGENCIA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido