Your browser doesn't support javascript.
loading
Relationships of Self-reported Opioid Use and Misuse and Pain Severity With Probable Major Depression Among Participants With Spinal Cord Injury.
Krause, James S; Dismuke-Greer, Clara E; DiPiro, Nicole D; Clark, Jillian M R; Laursen-Roesler, Jon.
Afiliación
  • Krause JS; College of Health Professions, Medical University of South Carolina, Charleston, SC. Electronic address: krause@musc.edu.
  • Dismuke-Greer CE; Health Economics Resource Center, Palo Alto Veterans Affairs Health Care, Menlo Park, CA.
  • DiPiro ND; College of Health Professions, Medical University of South Carolina, Charleston, SC.
  • Clark JMR; College of Health Professions, Medical University of South Carolina, Charleston, SC.
  • Laursen-Roesler J; Saint Mary's University of Minnesota, Minneapolis, MN, USA.
Arch Phys Med Rehabil ; 105(8): 1506-1512, 2024 Aug.
Article en En | MEDLINE | ID: mdl-38527688
ABSTRACT

OBJECTIVES:

To examine the relations of pain intensity, opioid use, and opioid misuse with depressive symptom severity and probable major depression (PMD) among participants with spinal cord injuries (SCI), controlling for demographic, injury, and socioeconomic characteristics. STUDY

DESIGN:

Cohort study.

SETTING:

Medical University in the Southeastern United States (US).

PARTICIPANTS:

Participants (N=918) were identified from 1 of 2 sources including a specialty hospital and a state-based surveillance system in the Southeastern US. Participants were a minimum of 18 years old at enrollment and had SCI with non-complete recovery. Participants were on average 57.5 years old at the time of the study and an average of 24.4 years post SCI onset.

INTERVENTIONS:

Not applicable. MAIN OUTCOME

MEASURES:

Participants completed a self-report assessment that included frequency of prescription opioid use and misuse, based on the National Survey on Drug Use and Health (NSDUH), and the PHQ - 9 to measure depressive symptom severity and PMD.

RESULTS:

Opioid use, opioid misuse, and pain intensity were related to elevated depressive symptom severity and higher odds of PMD. Non-Hispanic Blacks had fewer depressive symptoms and lower odds of PMD, as did those with higher incomes. Veterans had lower risk of PMD, whereas ambulatory participants had a higher risk of PMD. Age at SCI onset had a mixed pattern of significance, whereas years of education and years since injury were not significant.

CONCLUSIONS:

The relation between pain intensity with depressive symptom severity and PMD was profound, consistent with the biopsychosocial model of pain. The greater risk of PMD and higher depressive symptom severity among those using opioids and misusing opioids raises further concern about long-term prescription opioid use. Alternative treatments are needed.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de la Médula Espinal / Trastorno Depresivo Mayor / Autoinforme / Analgésicos Opioides / Trastornos Relacionados con Opioides Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Arch Phys Med Rehabil Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de la Médula Espinal / Trastorno Depresivo Mayor / Autoinforme / Analgésicos Opioides / Trastornos Relacionados con Opioides Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Arch Phys Med Rehabil Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos