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The relationship between cleft palate repair technique and audiological outcomes: A retrospective cohort study.
Kazemi, Tayebeh; Nabavizadeh, Sara S; Nadjmi, Nasser; Ahmadkhani, Alireza; Ghaemmaghami, Parvin; Kafaei, Ardavan; Faramarzi, Ali.
Afiliación
  • Kazemi T; Department of Otolaryngology, Otolaryngology Research Center Shiraz University of Medical Sciences Shiraz Iran.
  • Nabavizadeh SS; Department of Otolaryngology, Otolaryngology Research Center Shiraz University of Medical Sciences Shiraz Iran.
  • Nadjmi N; Department of Cranio-Maxillofacial Surgery Antwerp University Hospital Edegem Belgium.
  • Ahmadkhani A; Department of Maxillofacial Surgery ZMACK, AZ MONICA Antwerp Antwerp Belgium.
  • Ghaemmaghami P; Student Research Committee Shiraz University of Medical Sciences Shiraz Iran.
  • Kafaei A; Department of Biostatistics, School of nursing and midwifery, Shiraz University of Medical Sciences Shiraz Iran.
  • Faramarzi A; Student Research Committee Shiraz University of Medical Sciences Shiraz Iran.
Laryngoscope Investig Otolaryngol ; 9(2): e1237, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38525123
ABSTRACT

Objective:

Otitis media with effusion is common in children with cleft palates. This study aimed to investigate the link between palatal closure techniques and audiological outcomes.

Methods:

In this retrospective-prospective cohort study, we examined the relationship between palate repair techniques and hearing outcomes in children with cleft palates. From 2017 to 2022, 190 ears of 95 cleft patients were studied at the Cleft Lip and Palate Department of Shiraz University of Medical Sciences. Variables assessed included the surgical technique, cleft severity, auditory brainstem response (ABR) threshold, and tympanometry configuration.

Results:

The mean ABR improved from a prepalatoplasty value of 39.51(11.62) decibels (dB) to a postpalatoplasty mean of 26.61(11.60) dB (Cohen's d 1.12 [95% CI; 0.90-1.34]). Initially, 87.9% of the studied ears exhibited abnormal tympanometry, but this significantly decreased to 47% postsurgery (risk ratio 4.43 [95% CI; 1.20-16.43]). When compared with Sommerlad intravelar veloplasty, the Nadjmi modified Furlow palatoplasty was associated with a notably lower mean ABR (ß -6.58 [95% CI -10.43 to -2.73], p-value = .001) and a reduced frequency of abnormal tympanometry (odds ratio [OR] -1.10; 95% CI -1.85 to -0.36, p-value = .004). Factors like prepalatoplasty ABR, cleft palate severity, gender, and syndromic did not confound these findings.

Conclusions:

Although the Nadjmi modified Furlow palatoplasty showed better results, our findings indicate a significant improvement in ABR and tympanometry outcomes for both techniques. Future randomized controlled trials are suggested to confirm the influence of palatal closure techniques on audiological outcomes. Level of Evidence 3b.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Investig Otolaryngol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Investig Otolaryngol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos