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Topical oxygen therapy and singlet oxygen in wound healing: A scoping review.
Sýkorová, Martina; Moffatt, Christine Joy; Stentiford, Neil; Burian, Ewa Anna; Katsuhiro, Sasagaki; Wei, Yang.
Afiliación
  • Sýkorová M; Skin Integrity Research Group, School of Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
  • Moffatt CJ; The Institute of Care Excellence, Nottingham University Hospitals NHS Trust, City Hospital, Nottingham, UK.
  • Stentiford N; SOE Health Ltd, Nottingham, UK.
  • Burian EA; Department of Dermato-Venereology and Wound Healing Center, Bispebjerg Hospital, Copenhagen, Denmark.
  • Katsuhiro S; Medical Technologies Innovation Facility, Engineering Department, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
  • Wei Y; Medical Technologies Innovation Facility, Engineering Department, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
Int Wound J ; 21(4): e14846, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38522472
ABSTRACT
The aim of this scoping review was to provide an overview of current research into topical oxygen therapies including the under-researched singlet oxygen for wound healing. A scoping review was undertaken using five databases. After duplicates and ineligible studies were excluded, 49 studies were included for a narrative review. Out of the included 49 studies, 45 (91.8%) were published in the past 10 years (2013-2023) with 32 (65.3%) published in the past 5 years (2018-2023). Eight of the studies were systematic reviews and/or meta-analysis and 18 were RCTs. The search identified zero human RCTs on singlet oxygen, but one human cohort study and five studies in animals. There is evidence that topical oxygen therapy may be useful for the treatment of chronic wounds, mainly diabetic foot ulcers. Singlet oxygen has shown potential, but would need further confirmation in controlled human trials, including more research to understand the bio-properties.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pie Diabético / Oxígeno Singlete Límite: Humans Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pie Diabético / Oxígeno Singlete Límite: Humans Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido