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Langerhans cell histiocytosis in children with refractory diarrhoea and hypoalbuminaemia as the initial presentation: two case reports and a literature review.
Cao, Yi; Wu, Qing-Qing; Yan, Wei-Hui; Lu, Li-Na; Tao, Yi-Jing; Feng, Hai-Xia; Chu, Yi-Jing; Cai, Wei; Wang, Ying.
Afiliación
  • Cao Y; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Wu QQ; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Yan WH; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Lu LN; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Tao YJ; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Feng HX; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Chu YJ; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China.
  • Cai W; Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Rd, Shanghai, China. caiw1978@163.com.
  • Wang Y; Shanghai Institute for Pediatric Research, Shanghai, China. caiw1978@163.com.
BMC Pediatr ; 24(1): 203, 2024 Mar 22.
Article en En | MEDLINE | ID: mdl-38519924
ABSTRACT
Langerhans cell histiocytosis (LCH) involving the gastrointestinal tract is a rare condition for which clinical experience is limited. We describe the cases of two patients who initially presented with chronic diarrhoea, hypoproteinaemia, and intermittent fever. These findings suggest that in cases of refractory diarrhoea accompanied by recurrent hypoalbuminaemia, especially with abdominal rash, LCH should be considered. Gastrointestinal endoscopy, biopsy, and imaging studies are essential for obtaining a definitive diagnosis. This approach might be helpful for the early recognition of gastrointestinal tract involvement in LCH.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histiocitosis de Células de Langerhans / Hipoalbuminemia Límite: Child / Humans Idioma: En Revista: BMC Pediatr Asunto de la revista: PEDIATRIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Histiocitosis de Células de Langerhans / Hipoalbuminemia Límite: Child / Humans Idioma: En Revista: BMC Pediatr Asunto de la revista: PEDIATRIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido