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Post-Transplant Lymphoproliferative Disorders.
Dharnidharka, Vikas R; Ruzinova, Marianna B; Marks, Lianna J.
Afiliación
  • Dharnidharka VR; Division of Pediatric Nephrology, Hypertension and Apheresis, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. Electronic address: vikasD@wustl.edu.
  • Ruzinova MB; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
  • Marks LJ; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Stanford University School of Medicine, Palo Alto, CA.
Semin Nephrol ; 44(1): 151503, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38519279
ABSTRACT
Post-transplant lymphoproliferative disorders (PTLDs) are a heterogenous set of unregulated lymphoid cell proliferations after organ or tissue transplant. A majority of cases are associated with the Epstein-Barr virus and higher intensity of pharmacologic immunosuppression. The clinical presentations are numerous. The diagnosis is ideally by histology, except in cases where the tumor is inaccessible to biopsy. While some pre-emptive therapies and treatment strategies are available have reasonable success are available, they do not eliminate the high morbidity and significant mortality after PTLD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Virus de Epstein-Barr / Trastornos Linfoproliferativos Límite: Humans Idioma: En Revista: Semin Nephrol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Virus de Epstein-Barr / Trastornos Linfoproliferativos Límite: Humans Idioma: En Revista: Semin Nephrol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos