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Hyperuricemia research progress in model construction and traditional Chinese medicine interventions.
Zhou, Hongyan; Yang, Jingyi; Yuan, Xiaoqing; Song, Xinyu; Zhang, Xingcai; Cao, Ting; Zhang, Jiayu.
Afiliación
  • Zhou H; Institute of Chinese Medicine, Binzhou Medical University, Yantai, Shandong, China.
  • Yang J; School of Pharmacy, University of TCM, Jinan, Shandong, China.
  • Yuan X; Institute of Chinese Medicine, Binzhou Medical University, Yantai, Shandong, China.
  • Song X; Institute of Chinese Medicine, Binzhou Medical University, Yantai, Shandong, China.
  • Zhang X; Institute of Chinese Medicine, Binzhou Medical University, Yantai, Shandong, China.
  • Cao T; World Tea Organization, Cambridge, MA, United States.
  • Zhang J; The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Front Pharmacol ; 15: 1294755, 2024.
Article en En | MEDLINE | ID: mdl-38515855
ABSTRACT
Hyperuricemia (HUA), a severe metabolic disease derived from purine metabolism disorder, will lead to abnormally increased serum uric acid (SUA) levels in the body. Studies have shown that HUA is highly related to gout, hypertension, diabetes, coronary heart disease, chronic kidney diseases, and so on. Traditional Chinese medicine (TCM) shows excellent results in treating HUA because of its unique advantages of multi-metabolites and multi-targets. This article reports on the use of TCM components for uric acid (UA)-lowering activity with excellent efficacy and low side effects based on established HUA models. This work summarizes the advantages and limitations of various HUA disease models for efficacy evaluation. Applications of TCM in HUA treatment have also been discussed in detail. This paper reveals recent research progress on HUA in constructing evaluation models and systematic TCM interventions. It will provide a scientific reference for establishing the HUA model and suggest future TCM-related HUA studies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza