Your browser doesn't support javascript.
loading
Comparative phenotypic and genotypic analysis of community-acquired and hospital-acquired intra-abdominal infections among liver transplanted patients.
Elmanakhly, Arwa R; Safwat, Nesreen; Tohamy, Sally T K; Elsayed, Khaled M; ElSherif, Heba M; Elsayed, Mahitab; El-Tarabili, Reham M; Alhomrani, Majid; Alamri, Abdulhakeem S; Ghoneim, Mohammed M; Alshahrani, Mohammed A; Saif, Ahmed; Mansour, Abdallah T; Bendary, Mahmoud M.
Afiliación
  • Elmanakhly AR; Department of Microbiology and Immunology, Faculty of Pharmacy, Modern University for Technology and Information, Cairo 19648, Egypt.
  • Safwat N; Department of Microbiology and Immunology, Faculty of Pharmacy, Modern University for Technology and Information, Cairo 19648, Egypt.
  • Tohamy STK; Department of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 19648, Egypt.
  • Elsayed KM; Department of Microbiology, Faculty of Pharmacy, Misr international university (MIU), Cairo 19648, Egypt.
  • ElSherif HM; Department of Microbiology, Faculty of Pharmacy, Misr international university (MIU), Cairo 19648, Egypt.
  • Elsayed M; Department of clinical pharmacy, faculty of Pharmacy, Modern University for Technology and Information, Cairo 19648, Egypt.
  • El-Tarabili RM; Department of Bacteriology, Immunology and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
  • Alhomrani M; Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif 26432, Saudi Arabia.
  • Alamri AS; Reseacher center for health science, Deanship of Scientific Research, Taif University, Taif 26432, Saudi Arabia.
  • Ghoneim MM; Department of Clinical Laboratories Sciences, The Faculty of Applied Medical Science, Taif University, Taif 26432, Saudi Arabia.
  • Alshahrani MA; Reseacher center for health science, Deanship of Scientific Research, Taif University, Taif 26432, Saudi Arabia.
  • Saif A; Department of Pharmacy Practice, College of Pharmacy, Al Maarefa University, Ad Diriyah 13713, Saudi Arabia.
  • Mansour AT; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, P.O. Box 1988, Najran 61441, Saudi Arabia.
  • Bendary MM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 62217, Saudia Arabia.
J Appl Microbiol ; 135(4)2024 Apr 01.
Article en En | MEDLINE | ID: mdl-38515285
ABSTRACT

AIM:

During liver transplantation, both hospital-acquired (HA) and community-acquired (CA) intra-abdominal infections (IAIs) are involved causing life-threatening diseases. Therefore, comparative studies of aerobic and facultative anaerobic HA-IAIs and CA-IAIs after liver transplantation surgery are necessary. METHODS AND

RESULTS:

The species of detected isolates (310) from intra-abdominal fluid were identified and classified into hospital-acquired intra-abdominal infections (HA-IAIs) and community-acquired intra-abdominal infections (CA-IAIs). Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii were the most commonly detected species. The resistant phenotypes were commonly detected among the HA-IAIs; however, the virulent phenotypes were the predominant strains of CA-IAIs. Regrettably, the resistance profiles were shocking, indicating the inefficacy of monotherapy in treating these isolates. Therefore, we confirmed the use of empirical combination therapies of amikacin and meropenem for treating all IAIs (FICI ≤ 0.5). Unfortunately, the high diversity and low clonality of all identified HA and CA-IAIs were announced with D-value in the range of 0.992-1.

CONCLUSION:

This diversity proves that there are infinite numbers of infection sources inside and outside healthcare centers.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección Hospitalaria / Trasplante de Hígado / Infecciones Comunitarias Adquiridas / Infecciones Intraabdominales Límite: Humans Idioma: En Revista: J Appl Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección Hospitalaria / Trasplante de Hígado / Infecciones Comunitarias Adquiridas / Infecciones Intraabdominales Límite: Humans Idioma: En Revista: J Appl Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido