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Serum lactate normalization time associated with prolonged postoperative ileus after surgical management of the small bowel and/or mesenteric injuries.
Lee, Naa; Jeong, Euisung; Park, Yunchul; Jo, Younggoun; Kim, Jungchul; Jang, Hyunseok.
Afiliación
  • Lee N; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea.
  • Jeong E; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea.
  • Park Y; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea.
  • Jo Y; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea.
  • Kim J; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea.
  • Jang H; Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, 42 Jebong- ro, Dong-gu, Gwangju, 61469, Republic of Korea. bluetholic@naver.com.
BMC Surg ; 24(1): 94, 2024 Mar 21.
Article en En | MEDLINE | ID: mdl-38515100
ABSTRACT
BACK GROUND Determining the optimal timing of postoperative oral feeding in trauma patients who have undergone abdominal surgery with small bowel and/or mesenteric injuries is challenging. The aim of this study is to investigate serum lactate as a factor that can predict oral feeding tolerance and prolonged postoperative ileus (PPOI) in patients who underwent surgery for small bowel and/or mesenteric injury due to trauma.

METHODS:

The single center retrospective observational study was conducted on 367 patients who underwent surgery for small bowel and/or mesenteric injury between January 2013 and July 2021. The patient group was divided into two groups based on whether the peak serum lactate was over 2mmol/L (18 mg/dL). In the group of lactate > 2mmol/L, it was divided into prolonged postoperative ileus (PPOI) groups and groups rather than PPOI.

RESULTS:

Patients in the peak serum lactate > 2 group had tendency to use vasopressors, lower initial systolic blood pressure, larger number of packed red blood cells for 24 h, higher injury severity score, higher PPOI incidence, and a tendency for delayed oral intake tolerance. In peak serum lactate greater than 2 mmol/L group, the lactate normalization time (OR 1.699, p = 0.04), quantity of FFP transfusion for 24 h (OR 1.145, p = 0.012), and creatine kinase (OR 1.001, p = 0.023) were related to PPOI. The lactate normalization time had the highest correlation.

CONCLUSION:

In patients undergoing surgical management for small bowel and/or mesenteric injury after trauma, serum lactate normalization time affects oral intake tolerance and prolongs postoperative ileus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Ileus Límite: Humans Idioma: En Revista: BMC Surg Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Ileus Límite: Humans Idioma: En Revista: BMC Surg Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido