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Upfront stereotactic radiosurgery versus adjuvant radiosurgery for parasagittal and parafalcine meningiomas: a systematic review and meta-analysis.
De Nigris Vasconcellos, Fernando; Pichardo-Rojas, Pavel; Fieldler, Augusto Muller; Mashiach, Elad; Santhumayor, Brandon; Gorbachev, Jowah; Fountain, Hayes; Bandopadhay, Josh; Almeida, Timoteo; Sheehan, Jason.
Afiliación
  • De Nigris Vasconcellos F; Vivian L Smith, Department of Neurosurgery, Texas Institute for Restorative Neurotechnologies, UTHealth Houston, 6431 Fannin St, Houston, TX, 77030, USA. fervas1003@gmail.com.
  • Pichardo-Rojas P; Vivian L Smith, Department of Neurosurgery, Texas Institute for Restorative Neurotechnologies, UTHealth Houston, 6431 Fannin St, Houston, TX, 77030, USA.
  • Fieldler AM; Department of Neurosurgery, University of Miami, Miami, USA.
  • Mashiach E; Department of Neurosurgery, Rutgers University, Newark, USA.
  • Santhumayor B; Department of Neurosurgery, New York University, New York, USA.
  • Gorbachev J; Vivian L Smith, Department of Neurosurgery, Texas Institute for Restorative Neurotechnologies, UTHealth Houston, 6431 Fannin St, Houston, TX, 77030, USA.
  • Fountain H; Department of Neurosurgery, University of Miami, Miami, USA.
  • Bandopadhay J; Vivian L Smith, Department of Neurosurgery, Texas Institute for Restorative Neurotechnologies, UTHealth Houston, 6431 Fannin St, Houston, TX, 77030, USA.
  • Almeida T; Department of Neurosurgery, University of Miami, Miami, USA.
  • Sheehan J; Department of Neurosurgery, University of Virginia, Charlottesville, USA.
Neurosurg Rev ; 47(1): 127, 2024 Mar 22.
Article en En | MEDLINE | ID: mdl-38514580
ABSTRACT
Parafalcine and parasagittal (PFPS) are common locations for meningiomas. Surgical resection for these tumors, the first-line treatment, poses challenges due to their proximity to critical structures. This systematic review investigates the use of stereotactic radiosurgery (SRS) as a treatment for PFPS meningiomas, aiming to elucidate its safety and efficacy. The review adhered to PRISMA guidelines. Searches were conducted on MEDLINE, Embase, and Cochrane. Inclusion criteria involved studies on SRS for PFPS meningiomas, reporting procedure outcomes and complications. Tumors were presumed or confirmed to be WHO grade 1. Data was systematically extracted. Meta-analysis was performed where applicable. The review included data from eight studies, 821 patients with 878 lesions. Tumor control was achieved in greater than 80% of cases. Adverse radiation effects were reported in 7.3% of them. Recurrence and further surgical approach were observed in 17.1% and 9.2% of cases, respectively. Symptom improvement was noted in 33.2% of patients. Edema occurred in approximately 25.1% of patients. A subgroup of 283 patients had upfront SRS, achieving tumor control in approximately 97% of such cases. SRS is a safe and effective treatment for PFPS meningiomas, both as an adjuvant therapy and as an upfront treatment for often smaller tumors. Post-SRS edema can typically be managed medically and usually does not require further surgical intervention. Further studies should provide more specific data on PFPS meningiomas. The use of single and hypofractionated SRS for larger volume PFPS meningiomas should be more explored to better define the risks and benefits.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiocirugia / Neoplasias Meníngeas / Meningioma Límite: Humans Idioma: En Revista: Neurosurg Rev Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radiocirugia / Neoplasias Meníngeas / Meningioma Límite: Humans Idioma: En Revista: Neurosurg Rev Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania