Surveillance of Nipah virus in Pteropus medius of Kerala state, India, 2023.
Front Microbiol
; 15: 1342170, 2024.
Article
en En
| MEDLINE
| ID: mdl-38511004
ABSTRACT
Introduction:
Since 2018, the Indian state of Kerala has reported four Nipah virus (NiV) disease outbreaks, raising concerns about NiV spillover from bats to the human population. Considering this, a cross-sectional study was undertaken in the Pteropus medius bat population around the Nipah virus-affected regions of Kozhikode, Kerala, India, during February, July, and September 2023.Methods:
Throat swabs, rectal swabs, and organ samples were collected from bats to test for NiV using the real-time reverse transcriptase polymerase chain reaction (RT-PCR), while serum samples were screened for anti-Nipah IgG antibodies through ELISA.Results:
An overall seroprevalence of 20.9% was observed in 272 P. medius bats tested. The throat and rectal swab samples of 321 bats were negative for NiV RNA. However, 4 of 44 P. medius bats tested positive for NiV in their liver/spleen samples. The partial N gene retrieved showed more than 99% similarity with the earlier reported NiV genome from Kerala state, India.Discussion:
The findings of the study caution that there is a spillover risk in the region and necessary precautions should be taken.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Front Microbiol
Año:
2024
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Suiza