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Surface activation of Hastalex by vacuum argon plasma for cytocompatibility enhancement.
Slepicková Kasálková, Nikola; Rimpelová, Silvie; Vacek, Cyril; Fajstavr, Dominik; Svorcík, Václav; Sajdl, Petr; Slepicka, Petr.
Afiliación
  • Slepicková Kasálková N; Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Rimpelová S; Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Vacek C; Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Fajstavr D; Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Svorcík V; Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Sajdl P; Department of Power Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
  • Slepicka P; Department of Solid State Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech Republic.
Heliyon ; 10(6): e27816, 2024 Mar 30.
Article en En | MEDLINE | ID: mdl-38510028
ABSTRACT
Here, we present surface analysis and biocompatibility evaluation of novel composite material based on graphene oxide traded as Hastalex. First, the surface morphology and elemental analysis of the pristine material were examined by atomic force and scanning electron microscopies, and by energy-dispersive and X-ray photoelectron spectroscopies, respectively. The Hastalex surface was then modified by plasma (3 and 8 W with exposure times up to 240 s), the impact of which on the material surface wettability and morphology was further evaluated. In addition, the material aging was studied at room and elevated temperatures. Significant changes in surface roughness, morphology, and area were detected at the nanometer scale after plasma exposure. An increase in oxygen content due to the plasma exposure was observed both for 3 and 8 W. The plasma treatment had an outstanding effect on the cytocompatibility of Hastalex foil treated at both input powers of 3 and 8 W. The cell number of human MRC-5 fibroblasts on Hastalex foils exposed to plasma increased significantly compared to pristine Hastalex and even to tissue culture polystyrene. The plasma exposure also affected the fibroblasts' cell growth and shape.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido