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What Do We Know So Far About Ventricular Arrhythmias and Sudden Cardiac Death Prediction in the Mitral Valve Prolapse Population? Could Biomarkers Help Us Predict Their Occurrence?
Dziadosz, D; Danilowicz-Szymanowicz, L; Wejner-Mik, P; Budnik, M; Brzezinska, B; Duchnowski, P; Golinska-Grzybala, K; Jaworski, K; Jedlinski, I; Kamela, M; Kasprzak, J; Kowalczyk-Domagala, M; Kurnicka, K; Kustrzycka-Kratochwil, D; Mickiewicz, K; Mozenska, O; Oko-Sarnowska, Z; Plewka, M; Polewczyk, A; Uzieblo-Zyczkowska, B; Wierzbowska-Drabik, K; Wachnicka-Truty, R; Woloszyn-Horák, E; Szymanski, P; Gackowski, A; Mizia-Stec, K.
Afiliación
  • Dziadosz D; 1st Department of Cardiology, Faculty of Medicine, Medical University of Silesia, Katowice, Poland.
  • Danilowicz-Szymanowicz L; Centre of European Reference Network of Heart Diseases - ERN GUARD-HEART, 47 Ziolowa St, 40-635, Katowice, Poland.
  • Wejner-Mik P; Department of Cardiology and Electrotherapy, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.
  • Budnik M; 1st Department of Cardiology, Medical University of Lodz, Bieganski Hospital, Lódz, Poland.
  • Brzezinska B; 1st Chair and Department of Cardiology, Medical University of Warsaw, Central Clinical Hospital, 1a Banacha St, 02-97, Warsaw, Poland.
  • Duchnowski P; Department of Cardiology, T. Marciniak Hospital, Wroclaw, Poland.
  • Golinska-Grzybala K; Cardinal Wyszynski National Institute of Cardiology, 04-628, Warsaw, Poland.
  • Jaworski K; Dept of Coronary Disease and Heart Failure, Noninvasive Cardiovascular Laboratory, Medical College, Jagiellonian University, St. John Paul II Hospital, Cracow, Poland.
  • Jedlinski I; Department of Coronary Artery Disease and Cardiac Rehabilitation, National Institute of Cardiology, Warsaw, Poland.
  • Kamela M; Medicor, Powstanców Wielkopolskich 4, 61-895, Poznan, Poland.
  • Kasprzak J; Department of Cardiology, Hospital of the Ministry of Interior and Administration, Rzeszów, Poland.
  • Kowalczyk-Domagala M; 1st Department of Cardiology, Medical University of Lodz, Bieganski Hospital, Lódz, Poland.
  • Kurnicka K; Pediatric Cardiology Department, The Children's Memorial Health Institute, Warsaw, Poland.
  • Kustrzycka-Kratochwil D; Department of Internal Medicine and Cardiology, Medical University of Warsaw, Infant Jesus Clinical Hospital, Lindleya str. 4, 02-005, Warsaw, Poland.
  • Mickiewicz K; Department of Cardiology, Center for Heart Diseases, 4th Military Clinical Hospital, Weigla 5, 50-981, Wroclaw, Poland.
  • Mozenska O; Department of Cardiology, Medical University of Bialystok, 15-276, Bialystok, Poland.
  • Oko-Sarnowska Z; JO Medical Center, Quo Vadis 1/U6, 02-495, Warsaw, Poland.
  • Plewka M; Department of Cardiology, Poznan University of Medical Sciences, Wielkopolskie, 60-355, Poznan, Poland.
  • Polewczyk A; Department of Interventional Cardiology and Cardiac Arrhythmias, Military Medical Academy Memorial Teaching Hospital of the Medical University of Lodz, Lódz, Poland.
  • Uzieblo-Zyczkowska B; Department of Physiology, Pathophysiology and Clinical Immunology, Institute of Medical Sciences, Jan Kochanowski University, Zeromskiego 5, 25-369, Kielce, Poland.
  • Wierzbowska-Drabik K; Department of Cardiac Surgery, Swietokrzyskie Cardiology Center, Grunwaldzka 45, 25-736, Kielce, Poland.
  • Wachnicka-Truty R; Department of Cardiology and Internal Diseases, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
  • Woloszyn-Horák E; Department of Internal Medicine and Clinical Pharmacology, Medical University of Lodz, Lódz, Poland.
  • Szymanski P; Department of Cardiology and Internal Diseases, Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Gdynia, Poland.
  • Gackowski A; Second Department of Cardiology. Specialist Hospital in Zabrze, Medical University of Silesia, Curie-Sklodowskiej str. 10, Zabrze, Poland.
  • Mizia-Stec K; Center of Clinical Cardiology, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.
Curr Cardiol Rep ; 26(5): 245-268, 2024 May.
Article en En | MEDLINE | ID: mdl-38507154
ABSTRACT
PURPOSE OF THE REVIEW To summarize currently available data on the topic of mitral valve prolapse (MVP) and its correlation to the occurrence of atrial and ventricular arrhythmias. To assess the prognostic value of several diagnostic methods such as transthoracic echocardiography, transesophageal echocardiography, cardiac magnetic resonance, cardiac computed tomography, electrocardiography, and electrophysiology concerning arrhythmic episodes. To explore intra and extracellular biochemistry of the cardiovascular system and its biomarkers as diagnostic tools to predict rhythm disturbances in the MVP population. RECENT

FINDINGS:

MVP is a common and mainly benign valvular disorder. It affects 2-3% of the general population. MVP is a heterogeneous and highly variable phenomenon with three structural phenotypes myxomatous degeneration, fibroelastic deficiency, and forme fruste. Exercise intolerance, supraventricular tachycardia, and chest discomfort are the symptoms that are often paired with psychosomatic components. Though MVP is thought to be benign, the association between isolated MVP without mitral regurgitation (MR) or left ventricle dysfunction, with ventricular arrhythmia (VA) and sudden cardiac death (SCD) has been observed. The incidence of SCD in the MVP population is around 0.6% per year, which is 6 times higher than the occurrence of SCD in the general population. Often asymptomatic MVP population poses a challenge to screen for VA and prevent SCD. Therefore, it is crucial to carefully assess the risk of VA and SCD in patients with MVP with the use of various tools such as diagnostic imaging and biochemical and genetic screening.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Prolapso de la Válvula Mitral / Muerte Súbita Cardíaca Límite: Humans Idioma: En Revista: Curr Cardiol Rep Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Prolapso de la Válvula Mitral / Muerte Súbita Cardíaca Límite: Humans Idioma: En Revista: Curr Cardiol Rep Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos