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Transitions to polysubstance use: Prospective cohort study of adolescents in Australia.
Black, Nicola; Noghrehchi, Firouzeh; Yuen, Wing See; Aiken, Alexandra; Clare, Philip J; Chan, Gary; Kypri, Kypros; McBride, Nyanda; Bruno, Raimondo; Slade, Tim; Boland, Veronica; Mattick, Richard; Peacock, Amy.
Afiliación
  • Black N; Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia.
  • Noghrehchi F; Biomedical Informatics and Digital Health, The University of Sydney, Camperdown, Australia.
  • Yuen WS; National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
  • Aiken A; National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
  • Clare PJ; National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
  • Chan G; Prevention Research Collaboration, The University of Sydney, Camperdown, Australia.
  • Kypri K; National Centre for Youth Substance Use Research, The University of Queensland, Brisbane, Australia.
  • McBride N; School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.
  • Bruno R; National Drug Research Institute, Curtin University, Shenton Park, Australia.
  • Slade T; School of Psychological Sciences, University of Tasmania, Hobart, Australia.
  • Boland V; The Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Camperdown, Australia.
  • Mattick R; National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
  • Peacock A; National Drug and Alcohol Research Centre, University of New South Wales, Kensington, Australia.
Addiction ; 119(6): 1100-1110, 2024 06.
Article en En | MEDLINE | ID: mdl-38499496
ABSTRACT
BACKGROUND AND

AIMS:

Adolescent polysubstance use has been associated with adverse social and health outcomes. Our aim was to measure rates and transitions to polysubstance use during adolescence and identify factors associated with initiation and discontinuation of polysubstance use.

DESIGN:

Prospective cohort study. Multistate Markov modelling was used to estimate rates and identify correlates of transitions between substance use states. SETTING AND

PARTICIPANTS:

Adolescent-parent dyads (n = 1927; adolescents in grade 7, age ≈13 years) were recruited from Australian schools during 2010/11 (Wave 1). Adolescents were surveyed annually until 2016/17 (n = 1503; age ≈19 years; Wave 7) and parents were surveyed annually until 2014/15 (Wave 5). MEASUREMENTS Alcohol, tobacco, cannabis and 3,4-methylenedioxymethamphetamine (MDMA) use outcomes were collected at Waves 3-7. Potential confounders were collected at Waves 1-6 and consisted of sex, anxiety and depression symptoms and externalizing problems, parental monitoring, family conflict and cohesion, parental substance use and peer substance use. Covariates were age and family socioeconomic status.

FINDINGS:

Few adolescents engaged in polysubstance use at earlier waves (Wave 3 5%; Wave 4 8%), but proportions increased sharply across adolescence (Waves 5-7 17%, 24%, 36%). Rates of transitioning to polysubstance use increased with age, with few (<9%) adolescents transitioning out. More externalizing problems (odds ratio [OR] = 1.10; 99.6% confidence interval [CI] = 1.07-1.14), parental heavy episodic drinking (OR = 1.22; 99.6% CI = 1.07-1.40), parental illicit substance use (OR = 3.56; 99.6% CI = 1.43-8.86), peer alcohol use (OR = 5.68; 99.6% CI = 1.59-20.50) and peer smoking (OR = 4.18; 99.6% CI = 1.95-8.81) were associated with transitioning to polysubstance use.

CONCLUSIONS:

Polysubstance use in Australia appears to be rare during early adolescence but more common in later adolescence with low rates of transitioning out. Externalizing problems and greater parental and peer substance use are risk factors for adolescent polysubstance use that may be suitable intervention targets.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Relacionados con Sustancias Límite: Adolescent / Adult / Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Addiction Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos Relacionados con Sustancias Límite: Adolescent / Adult / Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Addiction Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido