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Dual disorder: does expert clinical experience support the rationale for cariprazine use?
Martinez-Raga, J; Bajouco, M; Kenzin, D; Sahlsten, J; De Berardis, D; Tzeferakos, G; Wagner, E; França, G; Johnsen, J; Roncero, C; Grunze, H.
Afiliación
  • Martinez-Raga J; Department of Psychiatry, University Hospital Doctor Peset, Valencia, Spain. heinz.grunze@icloud.com.
Eur Rev Med Pharmacol Sci ; 28(5): 2095-2106, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38497891
ABSTRACT
Comorbid substance use disorder (SUD) in patients with schizophrenia (dual disorder, DD) is a frequent occurrence in the psychiatric clinical practice and is positively associated with poorer outcomes. Despite a very high co-prevalence, clinical guidelines for SUD and severe mental illnesses tend to give limited consideration to co-existing disorders regarding diagnosis and management. This article is the result of a meeting held in February 2023 to discuss common challenges and best clinical practice initiatives for patients with schizophrenia and DD in different treatment settings. The authors identified issues in the clinical approach to DD in schizophrenia spectrum disorders and suggested the most suitable management based on their experience as a group of experts, identifying possible improvement areas. In conclusion, the panel recommends that individuals with DD should be cared for in a single center. Pharmacologic treatment in individuals with DD needing both control of symptoms related to schizophrenia spectrum disorders and substance withdrawal should ideally be based on using a non-sedative antipsychotic with anti-craving activity.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Abstinencia a Sustancias / Antipsicóticos Límite: Humans Idioma: En Revista: Eur Rev Med Pharmacol Sci Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Abstinencia a Sustancias / Antipsicóticos Límite: Humans Idioma: En Revista: Eur Rev Med Pharmacol Sci Asunto de la revista: FARMACOLOGIA / TOXICOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Italia