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Eco-Friendly CuO/Fe3O4 Nanocomposite synthesis, characterization, and cytotoxicity study.
Dwivedi, Poonam; Malik, Abdul; Fatima Hussain, Hafiza Zumra; Jatrana, Indu; Imtiyaz, Khalid; Rizvi, M M Alam; Mushtaque, Md; Khan, Azhar U; Alam, Mahboob; Rafatullah, Mohd.
Afiliación
  • Dwivedi P; Department of Chemistry, School of Basic Sciences, Jaipur National University, Jaipur, 302017 (Rajasthan) India.
  • Malik A; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
  • Fatima Hussain HZ; Department of Environmental, Biological and Pharmaceutical Science and Technology (DISTABiF), University of Campania 'Luigi Vanvitelli' Via Vivaldi 43, 81100 Caserta, Italy.
  • Jatrana I; Department of Chemistry, School of Basic Sciences, Jaipur National University, Jaipur, 302017 (Rajasthan) India.
  • Imtiyaz K; Department of Biosciences, Jamia Millia Islamia, New Delhi, 110025, India.
  • Rizvi MMA; Department of Biosciences, Jamia Millia Islamia, New Delhi, 110025, India.
  • Mushtaque M; Department of Chemistry, Millat College (A constituent colle ge of Lalit Narayan Mithila University), Darbhanga, Bihar, India.
  • Khan AU; Department of Chemistry, School of Basic Sciences, Jaipur National University, Jaipur, 302017 (Rajasthan) India.
  • Alam M; Division of Chemistry and Biotechnology, Dongguk University, 123, Dongdaero, Gyeongju-si 780714, Republic of Korea.
  • Rafatullah M; Environmental Technology Division, School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia.
Heliyon ; 10(6): e27787, 2024 Mar 30.
Article en En | MEDLINE | ID: mdl-38496878
ABSTRACT
The current study report a convenient, simple, and low cost approach for the biogenic synthesis of CuO/Fe3O4 nanocomposites (NCs) from pumpkin seeds extract and their vitro cytotoxicity. The characterization of finally obtained CuO/Fe3O4 nanocomposites (NCs) performed using UV-Visible, FT-IR, XRD, XPS, GC-MS, SEM-EDX and TEM analysis. The formation and elemental analysis were determined using the energy-dispersive X-ray (EDX) microanalysis technique. The formation of rod-like monoclinic and spherical, having size range 5 nm-20 nm confirmed by scanning electron microscope (SEM) and transmission electron microscopy (TEM) respectively. Finally, the MTT assay of the synthesized composites was evaluated for toxicity against cancerous cell lines HCT-116 (Colon cancer cell) and A549 (human lung adenocarcinoma cell). The synthesized composite material showed moderate (IC50 = 199 µg/mL) to low (IC50 = 445 µg/mL) activity against HCT-116 and A549 cell lines, respectively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido