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Correlation of serum IL-2 and IFN-γ levels with clinical prognosis of nasopharyngeal carcinoma patients and analysis of risk factors.
Guo, Siquan; Qin, Feng; Wang, Jiang; Ding, Yongqing; You, Jianqiang; Chao, Changjiang.
Afiliación
  • Guo S; Third Affiliated Hospital of Soochow University, Department of Otorhinolaryngology Head and Neck Surgery, Changzhou, China.
  • Qin F; Nanjing Medical University, Changzhou Third People's Hospital, Changzhou Medical Center, Department of Otorhinolaryngology Head and Neck Surgery, Changzhou, China.
  • Wang J; Third Affiliated Hospital of Soochow University, Department of Otorhinolaryngology Head and Neck Surgery, Changzhou, China.
  • Ding Y; First Affiliated Hospital of Hebei North University, Department of Otorhinolaryngology Head and Neck Surgery, Zhangjiakou, China.
  • You J; Third Affiliated Hospital of Soochow University, Department of Otorhinolaryngology Head and Neck Surgery, Changzhou, China.
  • Chao C; Third Affiliated Hospital of Soochow University, Department of Otorhinolaryngology Head and Neck Surgery, Changzhou, China.
J Med Biochem ; 43(1): 50-56, 2024 Jan 25.
Article en En | MEDLINE | ID: mdl-38496017
ABSTRACT

Background:

This study aims to investigate the correlation between serum levels of interleukin-2 (IL-2) and interferong (IFN-g) and the clinical prognosis of patients with nasopharyngeal carcinoma (NPC). Additionally, the study aims to analyse the risk factors associated with this correlation.

Methods:

The clinical data of 195 NPC patients admitted to our hospital from October 2020 to October 2022 were selected for a retrospective study. Based on the Glasgow score, patients were divided into two groups the good prognosis group (group g), consisting of patients who scored 0 points, and the poor prognosis group (group p), consisting of patients who scored 1-2 points. The levels of serum IL-2 and IFN-g were compared between the two groups, and the clinical values of serum IL-2 and IFN-g in the prognosis of patients were analysed. The clinical parameters of the patients were collected, and the risk factors affecting the prognosis of NPC were analysed by univariate and multivariate logistic regression.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Med Biochem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación:
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Med Biochem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: