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Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study.
Tikmani, Shiyam Sunder; Saleem, Sarah; Sadia, Afreen; M Bann, Carla; Bozdar, Muhammad Hayat; Raza, Jamal; Dhaded, Sangappa M; Goudar, Shivaprasad S; Gowdar, Guruparasad; Yasmin, Haleema; McClure, Elizabeth M; Goldenberg, Robert L.
Afiliación
  • Tikmani SS; The Aga Khan University, Karachi, Pakistan.
  • Saleem S; The Aga Khan University, Karachi, Pakistan.
  • Sadia A; The Aga Khan University, Karachi, Pakistan.
  • M Bann C; Research Triangle Institute (RTI) International, Durham, NC, USA.
  • Bozdar MH; National Institute of Child Health, Napier Quarter, Karachi, Pakistan.
  • Raza J; National Institute of Child Health, Napier Quarter, Karachi, Pakistan.
  • Dhaded SM; JN Medical College, Belagavi, India.
  • Goudar SS; JN Medical College, Belagavi, India.
  • Gowdar G; Bapuji Educational Association's JJM Medical College, Davangere, India.
  • Yasmin H; Jinnah Postgraduate Medical Center, Karachi, Pakistan.
  • McClure EM; Research Triangle Institute (RTI) International, Durham, NC, USA.
  • Goldenberg RL; Columbia University, New York, NY, USA.
Glob Pediatr Health ; 11: 2333794X241236617, 2024.
Article en En | MEDLINE | ID: mdl-38487208
ABSTRACT
Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature <35.5°C AHR 1.18 (1.00-1.39), and congenital malformations AHR 3.31 (2.64-4.16). Conclusion. This study identified key maternal and neonatal predictors of preterm neonatal mortality, emphasizing the need for targeted interventions and collaborative public health efforts to address disparities and regional variations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Glob Pediatr Health Año: 2024 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Glob Pediatr Health Año: 2024 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Estados Unidos