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Decoding semiotic minimal genome: a non-genocentric approach.
Gómez-Márquez, Carolina; Morales, J Alejandro; Romero-Gutiérrez, Teresa; Paredes, Omar; Borrayo, Ernesto.
Afiliación
  • Gómez-Márquez C; Biodigital Innovation Lab, Translational Bioengineering Department, Exact Sciences and Engineering University Center, Universidad de Guadalajara, Guadalajara, Mexico.
  • Morales JA; Biodigital Innovation Lab, Translational Bioengineering Department, Exact Sciences and Engineering University Center, Universidad de Guadalajara, Guadalajara, Mexico.
  • Romero-Gutiérrez T; Biodigital Innovation Lab, Translational Bioengineering Department, Exact Sciences and Engineering University Center, Universidad de Guadalajara, Guadalajara, Mexico.
  • Paredes O; Technological Innovation Department, Tlajomulco University Center, Universidad de Guadalajara, Guadalajara, Mexico.
  • Borrayo E; Biodigital Innovation Lab, Translational Bioengineering Department, Exact Sciences and Engineering University Center, Universidad de Guadalajara, Guadalajara, Mexico.
Front Microbiol ; 15: 1356050, 2024.
Article en En | MEDLINE | ID: mdl-38476952
ABSTRACT
The search for the minimum information required for an organism to sustain a cellular system network has rendered both the identification of a fixed number of known genes and those genes whose function remains to be identified. The approaches used in such search generally focus their analysis on coding genomic regions, based on the genome to proteic-product perspective. Such approaches leave other fundamental processes aside, mainly those that include higher-level information management. To cope with this limitation, a non-genocentric approach based on genomic sequence analysis using language processing tools and gene ontology may prove an effective strategy for the identification of those fundamental genomic elements for life autonomy. Additionally, this approach will provide us with an integrative analysis of the information value present in all genomic elements, regardless of their coding status.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Suiza