Your browser doesn't support javascript.
loading
Effects of flaxseed oil supplementation on metaphase II oocyte rates in IVF cycles with decreased ovarian reserve: a randomized controlled trial.
Chu, Qi; Yu, Yue-Xin; Zhang, Jing-Zi; Zhang, Yi-Tong; Yu, Jia-Ping.
Afiliación
  • Chu Q; Department of Reproductive Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
  • Yu YX; Department of Reproductive Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
  • Zhang JZ; Department of Reproductive Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
  • Zhang YT; Department of Reproductive Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
  • Yu JP; Department of Reproductive Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
Front Endocrinol (Lausanne) ; 15: 1280760, 2024.
Article en En | MEDLINE | ID: mdl-38469148
ABSTRACT

Background:

This study was designed to explore the effects of flaxseed oil on the metaphase II (MII) oocyte rates in women with decreased ovarian reserve (DOR).

Methods:

The women with DOR were divided into a study group (n = 108, flaxseed oil treatment) and a control group (n = 110, no treatment). All patients were treated with assisted reproductive technology (ART). Subsequently, the ART stimulation cycle parameters, embryo transfer (ET) results, and clinical reproductive outcomes were recorded. The influencing factors affecting the MII oocyte rate were analyzed using univariate analysis and multivariate analysis.

Results:

Flaxseed oil reduced the recombinant human follicle-stimulating hormone (r-hFSH) dosage and stimulation time and increased the peak estradiol (E2) concentration in DOR women during ART treatment. The MII oocyte rate, fertilization rate, cleavage rate, high-quality embryo rate, and blastocyst formation rate were increased after flaxseed oil intervention. The embryo implantation rate of the study group was higher than that of the control group (p = 0.05). Additionally, the female age [odds ratio (OR) 0.609, 95% confidence interval (CI) 0.52-0.72, p < 0.01] was the hindering factor of MII oocyte rate, while anti-Müllerian hormone (AMH; OR 100, 95% CI 20.31-495, p < 0.01), peak E2 concentration (OR 1.00, 95% CI 1.00-1.00, p = 0.01), and the intake of flaxseed oil (OR 2.51, 95% CI 1.06-5.93, p = 0.04) were the promoting factors for MII oocyte rate.

Conclusion:

Flaxseed oil improved ovarian response and the quality of oocytes and embryos, thereby increasing the fertilization rate and high-quality embryo rate in DOR patients. The use of flaxseed oil was positively correlated with MII oocyte rate in women with DOR. Clinical trial number https//www.chictr.org.cn/, identifier ChiCTR2300073785.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceite de Linaza / Reserva Ovárica Límite: Female / Humans Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceite de Linaza / Reserva Ovárica Límite: Female / Humans Idioma: En Revista: Front Endocrinol (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza