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Long-term trends in incidence, characteristics and prognosis of screen-detected and interval cancers in women participating in the Dutch breast cancer screening programme.
Ten Velde, Daniëlle E; Duijm, Lucien E M; van der Sangen, Maurice J C; Schipper, Robert-Jan; Tjan-Heijnen, Vivianne C G; Vreuls, Willem; Strobbe, Luc J A; Voogd, Adri C.
Afiliación
  • Ten Velde DE; Department of Epidemiology, Maastricht University, Maastricht, the Netherlands.
  • Duijm LEM; Department of Radiology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
  • van der Sangen MJC; Department of Radiotherapy, Catharina Hospital, Eindhoven, the Netherlands.
  • Schipper RJ; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
  • Tjan-Heijnen VCG; Department of Medical Oncology, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Vreuls W; Department of Pathology, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
  • Strobbe LJA; Department of Surgery, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
  • Voogd AC; Department of Epidemiology, Maastricht University, Maastricht, the Netherlands. adri.voogd@maastrichtuniversity.nl.
Br J Cancer ; 130(9): 1561-1570, 2024 May.
Article en En | MEDLINE | ID: mdl-38467826
ABSTRACT

BACKGROUND:

No studies are available in which changes over time in characteristics and prognosis of patients with interval breast cancers (ICs) and screen-detected breast cancers (SDCs) have been compared. The aim was to study these trends between 1995 and 2018.

METHODS:

All women with invasive SDCs (N = 4290) and ICs (N = 1352), diagnosed in a southern mammography screening region in the Netherlands, were included and followed until date of death or 31 December 2022.

RESULTS:

The 5-year overall survival rate of women with SDCs increased from 91.4% for those diagnosed in 1995-1999 to 95.0% for those diagnosed in 2013-2018 (P < 0.001), and from 74.8 to 91.6% (P < 0.001) in the same periods for those with ICs. A similar trend was observed for the 10-year survival rates. After adjustment for changes in tumour characteristics, the hazard ratio (HR) for overall survival was 0.47 (95% confidence interval (CI) 0.38-0.59) for women with SDCs diagnosed in the period 2013-2018, compared to the women diagnosed in the period 1995-1999. For the women with ICs this HR was 0.27 (95% CI 0.19-0.40).

CONCLUSION:

The prognosis of women with ICs has improved rapidly since 1995 and is now almost similar to that of women with SDCs.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Mamografía / Detección Precoz del Cáncer Límite: Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Mamografía / Detección Precoz del Cáncer Límite: Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido