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TB index case tracing in the Roma community in the Czech Republic.
Dolezalová, Karolína; Malisková, Beatrix; Honegerová, Michaela; Hromádková, Michaela; Wallenfels, Jirí.
Afiliación
  • Dolezalová K; Clinic of Paediatrics, First Faculty of Medicine, Charles University in Prague and Thomayer University Hospital, Prague, Czech Republic.
  • Malisková B; Pneumology Department, Hospital Mladá Boleslav, Mlada Boleslav, Czech Republic.
  • Honegerová M; Regional Public Health Institute of Central Bohemia, Central Bohemia, Czech Republic.
  • Hromádková M; National Reference Laboratory for Mycobacteria, National Institute of Public Health, Praha, Czech Republic.
  • Wallenfels J; National Tuberculosis Surveillance Unit, University Hospital Bulovka, Prague, Czech Republic.
Epidemiol Infect ; 152: e45, 2024 Mar 11.
Article en En | MEDLINE | ID: mdl-38465380
ABSTRACT
Tuberculosis (TB) contact tracing and TB preventive treatment are key tools in preventing the transmission of TB with the aim of eliminating the disease. Our study seeks to demonstrate how the infection spread from an individual patient to the entire community and how proactive contact tracing facilitated prompt diagnosis and treatment. Our work was conducted as a retrospective analysis of the spread of TB infection within the Roma community in the Czech Republic, following the case of an index patient who succumbed to pulmonary TB. Several levels of care and preventive and treatment measures are outlined. Confirming the identity of the Mycobacterium tuberculosis strain was achieved using molecular methods. Among the 39 individuals examined, TB disease was detected in eight patients and TB infection was detected in six patients. The investigation of contacts within this group yielded positive results in 36% of cases, necessitating treatment. The study's findings provide evidence that actively tracing individuals at risk can lead to early detection of cases, prompt treatment, and prevention of further disease transmission. The study also indicates that the highest risk of infection occurs within the sick person's household and that young children under the age of 5 are most susceptible to falling ill.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Tuberculosis Pulmonar / Romaní / Tuberculosis Latente Límite: Child, preschool / Humans País/Región como asunto: Europa Idioma: En Revista: Epidemiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / EPIDEMIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Tuberculosis Pulmonar / Romaní / Tuberculosis Latente Límite: Child, preschool / Humans País/Región como asunto: Europa Idioma: En Revista: Epidemiol Infect Asunto de la revista: DOENCAS TRANSMISSIVEIS / EPIDEMIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido