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COVID-19 and Mortality in the Global Surgical Population: A Systematic Review and Meta-Analysis.
Obidike, Prisca; Chang, Allison; Calisi, Olivia; Lee, Jungeun J; Ssentongo, Paddy; Ssentongo, Anna E; Oh, John S.
Afiliación
  • Obidike P; Department of General Surgery, University of Virginia, Charlottesville, Virginia; Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Chang A; Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Calisi O; Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Lee JJ; Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Ssentongo P; Department of Medicine, Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania; Department of Public Health Sciences, Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Ssentongo AE; Department of Public Health Sciences, Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania; Division of Trauma Surgery, Department of Surgery, Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania.
  • Oh JS; Division of Trauma Surgery, Department of Surgery, Penn State College of Medicine and Milton S. Hershey Medical Center, Hershey, Pennsylvania. Electronic address: johnoh1@pennstatehealth.psu.edu.
J Surg Res ; 297: 88-100, 2024 May.
Article en En | MEDLINE | ID: mdl-38460454
ABSTRACT

INTRODUCTION:

To date, no systematic review or meta-analysis has comprehensively estimated the risk of mortality by surgery type on an international scale. We aim to delineate the risk of mortality in patients with COVID-19 who undergo surgery.

METHODS:

PubMed (MEDLINE), Scopus, OVID, the World Health Organization Global Literature on Coronavirus Disease, and Corona-Central databases were searched from December 2019 through January 2022. Studies providing data on mortality in patients undergoing surgery were included. The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines for abstracting data were followed and performed independently by two reviewers. The main outcome was mortality in patients with COVID-19.

RESULTS:

Of a total of 4023 studies identified, 46 studies with 80,015 patients met our inclusion criteria. The mean age was 67 y; 57% were male. Surgery types included general (14.9%), orthopedic (23.4%), vascular (6.4%), thoracic (10.6%), and urologic (8.5%). Patients undergoing surgery with COVID-19 elicited a nine-fold increased risk of mortality (relative risk [RR] 8.99, 95% confidence interval [CI] 4.96-16.32) over those without COVID-19. In low-income and middle-income countries (RR 16.04, 95% CI 4.59-56.12), the mortality risk was twice as high compared to high-income countries (RR 7.50, 95% CI 4.30-13.09).

CONCLUSIONS:

Mortality risk in surgical patients with COVID-19 compared to those without is increased almost 10-fold. The risk was highest in low-income and middle-income countries compared to high-income countries, suggesting a disproportionate effect of the pandemic on resource-constrained regions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos Operativos / Salud Global / COVID-19 Límite: Humans Idioma: En Revista: J Surg Res Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos Operativos / Salud Global / COVID-19 Límite: Humans Idioma: En Revista: J Surg Res Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos