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An Integrated Care Pathway for depression in adolescents: protocol for a Type 1 Hybrid Effectiveness-implementation, Non-randomized, Cluster Controlled Trial.
Courtney, Darren B; Barwick, Melanie; Amani, Bahar; Greenblatt, Andrea T; Aitken, Madison; Krause, Karolin R; Andrade, Brendan F; Bennett, Kathryn; Cleverley, Kristin; Uliaszek, Amanda A; de Oliveira, Claire; Hawke, Lisa D; Henderson, Jo; Wang, Wei; Watson, Priya; Gajaria, Amy; Newton, Amanda S; Ameis, Stephanie; Relihan, Jacqueline; Prebeg, Matthew; Chen, Sheng; Szatmari, Peter.
Afiliación
  • Courtney DB; Centre for Addiction and Mental Health, Toronto, ON, Canada. darren.courtney@camh.ca.
  • Barwick M; University of Toronto, Toronto, ON, Canada. darren.courtney@camh.ca.
  • Amani B; Cundill Centre for Child and Youth Depression, Toronto, ON, Canada. darren.courtney@camh.ca.
  • Greenblatt AT; University of Toronto, Toronto, ON, Canada.
  • Aitken M; Hospital for Sick Children, Toronto, ON, Canada.
  • Krause KR; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Andrade BF; Cundill Centre for Child and Youth Depression, Toronto, ON, Canada.
  • Bennett K; University of Toronto, Toronto, ON, Canada.
  • Cleverley K; Hospital for Sick Children, Toronto, ON, Canada.
  • Uliaszek AA; Cundill Centre for Child and Youth Depression, Toronto, ON, Canada.
  • de Oliveira C; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Hawke LD; Cundill Centre for Child and Youth Depression, Toronto, ON, Canada.
  • Henderson J; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Wang W; University of Toronto, Toronto, ON, Canada.
  • Watson P; Department of Health Research Methods, Evidence, and Impact (Formerly Clinical Epidemiology and Biostatistics), McMaster University, McMaster University Faculty of Health Sciences, Hamilton, ON, Canada.
  • Gajaria A; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Newton AS; University of Toronto, Toronto, ON, Canada.
  • Ameis S; University of Toronto, Toronto, ON, Canada.
  • Relihan J; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Prebeg M; Centre for Addiction and Mental Health, Toronto, ON, Canada.
  • Chen S; University of Toronto, Toronto, ON, Canada.
  • Szatmari P; Centre for Addiction and Mental Health, Toronto, ON, Canada.
BMC Psychiatry ; 24(1): 193, 2024 Mar 08.
Article en En | MEDLINE | ID: mdl-38459453
ABSTRACT

INTRODUCTION:

Our group developed an Integrated Care Pathway to facilitate the delivery of evidence-based care for adolescents experiencing depression called CARIBOU-2 (Care for Adolescents who Receive Information 'Bout OUtcomes, 2nd iteration). The core pathway components are assessment, psychoeducation, psychotherapy options, medication options, caregiver support, measurement-based care team reviews and graduation. We aim to test the clinical and implementation effectiveness of the CARIBOU-2 pathway relative to treatment-as-usual (TAU) in community mental health settings. METHODS AND

ANALYSIS:

We will use a Type 1 Hybrid Effectiveness-Implementation, Non-randomized Cluster Controlled Trial Design. Primary participants will be adolescents (planned n = 300, aged 13-18 years) with depressive symptoms, presenting to one of six community mental health agencies. All sites will begin in the TAU condition and transition to the CARIBOU-2 intervention after enrolling 25 adolescents. The primary clinical outcome is the rate of change of depressive symptoms from baseline to the 24-week endpoint using the Childhood Depression Rating Scale-Revised (CDRS-R). Generalized mixed effects modelling will be conducted to compare this outcome between intervention types. Our primary hypothesis is that there will be a greater rate of reduction in depressive symptoms in the group receiving the CARIBOU-2 intervention relative to TAU over 24 weeks as per the CDRS-R. Implementation outcomes will also be examined, including clinician fidelity to the pathway and its components, and cost-effectiveness. ETHICS AND DISSEMINATION Research ethics board approvals have been obtained. Should our results support our hypotheses, systematic implementation of the CARIBOU-2 intervention in other community mental health agencies would be indicated.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reno / Prestación Integrada de Atención de Salud Límite: Adolescent / Animals / Child / Humans Idioma: En Revista: BMC Psychiatry Asunto de la revista: PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reno / Prestación Integrada de Atención de Salud Límite: Adolescent / Animals / Child / Humans Idioma: En Revista: BMC Psychiatry Asunto de la revista: PSIQUIATRIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido