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Mediterranean-style dietary interventions in adults with cancer: a systematic review of the methodological approaches, feasibility, and preliminary efficacy.
McHugh, Aoife; O'Connell, Ellie; Gurd, Bridie; Rae, Paige; George, Elena S; Kleckner, Amber S; Baguley, Brenton J.
Afiliación
  • McHugh A; School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
  • O'Connell E; School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
  • Gurd B; School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
  • Rae P; School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
  • George ES; School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
  • Kleckner AS; Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, Australia.
  • Baguley BJ; Department of Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, MD, USA.
Eur J Clin Nutr ; 78(6): 463-476, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38459161
ABSTRACT

BACKGROUND:

Cancer and its treatments can lead to excess body fat, decreases in lean mass, cardiotoxicity, and other side effects. The Mediterranean diet (MED-diet) has the potential to improve clinical and supportive care outcomes. The aim of this systematic review was to evaluate the feasibility, safety, and efficacy of the MED-diet on health outcomes in adults with cancer.

METHODS:

Three databases were searched from inception to February 2023. Eligible studies included randomised controlled trials testing a MED-diet intervention among adults with cancer. Within- and between-group differences for adherence, dietary intake and health outcomes were extracted.

RESULTS:

Fifteen studies describing fourteen interventions were included, and there were considerable differences in study design and implementation of the MED-diet. Studies were predominately in women with a history of breast cancer. The MED-diet was safe with no adverse events reported, and feasible with high adherence and/or increases in MED-diet-compliant foods. The MED-diet when applied with an energy restriction below estimated requirements for weight loss demonstrated reductions in body weight (range -3.9 kg to -0.7 kg). Interventions that showed significant reductions in body weight also improved quality of life. There is limited evidence to evaluating the MED-diet on cardiovascular and inflammatory markers, and heterogenous MED-diet prescriptions impede definitive conclusions on these health outcomes.

CONCLUSION:

The MED-diet was feasible and safe for adults with cancer. There were reported benefits for weight loss following a MED-diet when an energy restriction was applied, however further evaluation to determine the effects on cardiometabolic biomarkers and other outcomes are required.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dieta Mediterránea / Neoplasias Límite: Adult / Female / Humans / Male Idioma: En Revista: Eur J Clin Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dieta Mediterránea / Neoplasias Límite: Adult / Female / Humans / Male Idioma: En Revista: Eur J Clin Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido