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Trends in presumed drug overdose out-of-hospital cardiac arrests in San Francisco, 2015-2023.
Wang, Ralph C; Montoy, Juan Carlos C; Rodriguez, Robert M; Menegazzi, James J; Lacocque, Jeremy; Dillon, David G.
Afiliación
  • Wang RC; Department of Emergency Medicine, University of California, San Francisco, USA. Electronic address: ralph.wang@ucsf.edu.
  • Montoy JCC; Department of Emergency Medicine, University of California, San Francisco, USA.
  • Rodriguez RM; Department of Emergency Medicine, University of California, San Francisco, USA.
  • Menegazzi JJ; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, USA.
  • Lacocque J; Department of Emergency Medicine, University of California, San Francisco, USA.
  • Dillon DG; Department of Emergency Medicine, University of California, Davis, USA.
Resuscitation ; 198: 110159, 2024 05.
Article en En | MEDLINE | ID: mdl-38458415
ABSTRACT

INTRODUCTION:

Estimates of the prevalence of drug-related out of hospital cardiac arrest (OHCA) vary, ranging from 1.8% to 10.0% of medical OHCA. However, studies conducted prior to the recent wave of fentanyl deaths likely underestimate the current prevalence of drug-related OHCA. We evaluated recent trends in drug-related OHCA, hypothesizing that the proportion of presumed drug-related OHCA treated by emergency medical services (EMS) has increased since 2015.

METHODS:

We conducted a retrospective analysis of OHCA patients treated by EMS providers in San Francisco, California between 2015 and 2023. Participants included OHCA cases in which resuscitation was attempted by EMS. The study exposure was the year of arrest. Our primary outcome was the occurrence of drug-related OHCA, defined as the EMS impression of OHCA caused by a presumed or known overdose of medication(s) or drug(s).

RESULTS:

From 2015 to 2023, 5044 OHCA resuscitations attended by EMS (average 561 per year) met inclusion criteria. The median age was 65 (IQR 50-79); 3508 (69.6%) were male. The EMS impression of arrest etiology was drug-related in 446/5044 (8.8%) of OHCA. The prevalence of presumed drug-related OHCA increased significantly each year from 1% in 2015 to 17.6% in 2023 (p-value for trend = 0.0001). After adjustment, presumed drug-related OHCA increased by 30% each year from 2015-2023.

CONCLUSION:

Drug-related OHCA is an increasingly common etiology of OHCA. In 2023, one in six OHCA was presumed to be drug related. Among participants less than 60 years old, one in three OHCA was presumed to be drug related.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Servicios Médicos de Urgencia / Paro Cardíaco Extrahospitalario / Sobredosis de Droga Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Resuscitation Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Servicios Médicos de Urgencia / Paro Cardíaco Extrahospitalario / Sobredosis de Droga Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Resuscitation Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda