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Dosimetry and efficiency comparison of knowledge-based and manual planning using volumetric modulated arc therapy for craniospinal irradiation.
Tsai, Wei-Ta; Hsieh, Hui-Ling; Hung, Shih-Kai; Zeng, Chi-Fu; Lee, Ming-Fen; Lin, Po-Hao; Lin, Chia-Yi; Li, Wei-Chih; Chiou, Wen-Yen; Wu, Tung-Hsin.
Afiliación
  • Tsai WT; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
  • Hsieh HL; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Hung SK; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Zeng CF; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Lee MF; School of Medicine, Tzu Chi University, Hualien, Taiwan.
  • Lin PH; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Lin CY; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Li WC; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Chiou WY; Department of Radiation Oncology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
  • Wu TH; Departments of Radiation Oncology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.
Radiol Oncol ; 58(2): 289-299, 2024 06 01.
Article en En | MEDLINE | ID: mdl-38452341
ABSTRACT

BACKGROUND:

Craniospinal irradiation (CSI) poses a challenge to treatment planning due to the large target, field junction, and multiple organs at risk (OARs) involved. The aim of this study was to evaluate the performance of knowledge-based planning (KBP) in CSI by comparing original manual plans (MP), KBP RapidPlan initial plans (RPI), and KBP RapidPlan final plans (RPF), which received further re-optimization to meet the dose constraints. PATIENTS AND

METHODS:

Dose distributions in the target were evaluated in terms of coverage, mean dose, conformity index (CI), and homogeneity index (HI). The dosimetric results of OARs, planning time, and monitor unit (MU) were evaluated.

RESULTS:

All MP and RPF plans met the plan goals, and 89.36% of RPI plans met the plan goals. The Wilcoxon tests showed comparable target coverage, CI, and HI for the MP and RPF groups; however, worst plan quality was demonstrated in the RPI plans than in MP and RPF. For the OARs, RPF and RPI groups had better dosimetric results than the MP group (P < 0.05 for optic nerves, eyes, parotid glands, and heart). The planning time was significantly reduced by the KBP from an average of 677.80 min in MP to 227.66 min (P < 0.05) and 307.76 min (P < 0.05) in RPI, and RPF, respectively. MU was not significantly different between these three groups.

CONCLUSIONS:

The KBP can significantly reduce planning time in CSI. Manual re-optimization after the initial KBP is recommended to enhance the plan quality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dosificación Radioterapéutica / Planificación de la Radioterapia Asistida por Computador / Radioterapia de Intensidad Modulada / Órganos en Riesgo / Irradiación Craneoespinal Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Radiol Oncol Año: 2024 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Polonia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dosificación Radioterapéutica / Planificación de la Radioterapia Asistida por Computador / Radioterapia de Intensidad Modulada / Órganos en Riesgo / Irradiación Craneoespinal Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Radiol Oncol Año: 2024 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Polonia