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Assessing the Impact of Bariatric Surgery on Retinol-Binding Protein 4 (RBP4): A Systematic Review and Meta-Analysis.
Bidares, Matin; Safari-Kish, Borna; Malekzadeh-Shoushtari, Hesam; Azarbayejani, Niloufar; Nosouhi, Golnaz; Aziz, Mahsa.
Afiliación
  • Bidares M; Clinical Research Development Center, Najafabad Branch, Islamic Azad University, Najafabad, Postal Code: 8514143131, Iran.
  • Safari-Kish B; Clinical Research Development Center, Najafabad Branch, Islamic Azad University, Najafabad, Postal Code: 8514143131, Iran. borna.safari.93@gmail.com.
  • Malekzadeh-Shoushtari H; School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Postal Code: 6135715753, Iran.
  • Azarbayejani N; School of Medicine, Sanandaj University of Medical Sciences, Sanandaj, Postal Code: 6618634683, Kurdistan, Iran.
  • Nosouhi G; Clinical Research Development Center, Najafabad Branch, Islamic Azad University, Najafabad, Postal Code: 8514143131, Iran.
  • Aziz M; Clinical Research Development Center, Najafabad Branch, Islamic Azad University, Najafabad, Postal Code: 8514143131, Iran.
Obes Surg ; 34(5): 1855-1865, 2024 May.
Article en En | MEDLINE | ID: mdl-38451368
ABSTRACT
This study aimed to analyze changes in retinol-binding protein 4 (RBP4) levels before and after bariatric surgery in obese individuals. Bariatric surgery is a safe and effective treatment for morbid obesity, impacting molecules like RBP4. A systematic review and meta-analysis of 12 relevant studies were conducted, utilizing databases such as PubMed, Cochrane Central, Web of Science, and Scopus. Significant differences in RBP4, glucose, and BMI levels pre- and post-surgery were observed. Meta-regression analysis explored associations with age, pre-BMI, triglycerides, glucose, and post-insulin levels. Findings suggest RBP4 may improve insulin sensitivity after bariatric surgery, warranting further investigation as a potential pharmacotherapeutic target. These results highlight the importance of understanding RBP4's role in the context of bariatric surgery and its implications for improving metabolic health in obese individuals.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Resistencia a la Insulina / Cirugía Bariátrica Límite: Humans Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Resistencia a la Insulina / Cirugía Bariátrica Límite: Humans Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos