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Differential sensitivity of intraindividual variability dispersion and global cognition in the prediction of functional outcomes and mortality in precariously housed and homeless adults.
Blumberg, Michelle J; Petersson, Anna M; Jones, Paul W; Jones, Andrea A; Panenka, William J; Leonova, Olga; Vila-Rodriguez, Fidel; Lang, Donna J; Barr, Alasdair M; MacEwan, G William; Buchanan, Tari; Honer, William G; Gicas, Kristina M.
Afiliación
  • Blumberg MJ; Department of Psychology, York University, Toronto, Canada.
  • Petersson AM; Department of Psychology, Simon Fraser University, Burnaby, Canada.
  • Jones PW; Department of Psychology, Simon Fraser University, Burnaby, Canada.
  • Jones AA; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Panenka WJ; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Leonova O; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Vila-Rodriguez F; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Lang DJ; Department of Radiology, University of British Columbia, Vancouver, Canada.
  • Barr AM; Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, Canada.
  • MacEwan GW; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Buchanan T; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Honer WG; Department of Psychiatry, University of British Columbia, Vancouver, Canada.
  • Gicas KM; Department of Psychology, York University, Toronto, Canada.
Clin Neuropsychol ; : 1-24, 2024 Mar 05.
Article en En | MEDLINE | ID: mdl-38444068
ABSTRACT

OBJECTIVE:

To examine cognitive intraindividual variability (IIV) dispersion as a predictor of everyday functioning and mortality in persons who are homeless or precariously housed.

METHOD:

Participants were 407 community-dwelling adults, followed for up to 13 years. Neurocognition was assessed at baseline and IIV dispersion was derived using a battery of standardized tests. Functional outcomes (social, physical) were obtained at baseline and last follow-up. Mortality was confirmed with Coroner's reports and hospital records (N = 103 deaths). Linear regressions were used to predict current social and physical functioning from IIV dispersion. Repeated measures Analysis of Covariance were used to predict long-term change in functioning. Cox regression models examined the relation between IIV dispersion and mortality. Covariates included global cognition (i.e. mean-level performance), age, education, and physical comorbidities.

RESULTS:

Higher IIV dispersion predicted poorer current physical functioning (B = -0.46 p = .010), while higher global cognition predicted better current (B = 0.21, p = .015) and change in social functioning over a period of up to 13 years (F = 4.23, p = .040). Global cognition, but not IIV dispersion, predicted mortality in individuals under 55 years old (HR = 0.50, p = .013).

CONCLUSIONS:

Our findings suggest that indices of neurocognitive functioning (i.e. IIV dispersion and global cognition) may be differentially related to discrete dimensions of functional outcomes in an at-risk population. IIV dispersion may be a complimentary marker of emergent physical health dysfunction in precariously housed adults and may be best used in conjunction with traditional neuropsychological indices.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Neuropsychol Asunto de la revista: NEUROLOGIA / PSICOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Neuropsychol Asunto de la revista: NEUROLOGIA / PSICOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido