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Comparative study of sleep and circadian rhythms in patients presenting unipolar or bipolar major depressive episodes.
Leseur, Jeanne; Boiret, Charlotte; Romier, Alix; Bazin, Balthazar; Basquin, Louise; Stern, Emilie; Pineau, Guillaume; Lejoyeux, Michel; Geoffroy, Pierre A; Maruani, Julia.
Afiliación
  • Leseur J; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France. Electronic address: jeanne-leseur@outlook.fr.
  • Boiret C; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, Paris F-75019, France.
  • Romier A; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, Paris F-75019, France.
  • Bazin B; Centre ChronoS, GHU Paris, Psychiatry & Neurosciences, 1 rue Cabanis, Paris 75014, France.
  • Basquin L; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France.
  • Stern E; Centre ChronoS, GHU Paris, Psychiatry & Neurosciences, 1 rue Cabanis, Paris 75014, France.
  • Pineau G; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France.
  • Lejoyeux M; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, Paris F-75019, France; Centre ChronoS, GHU Paris, Psychiatry & Neurosciences
  • Geoffroy PA; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, Paris F-75019, France; Centre ChronoS, GHU Paris, Psychiatry & Neurosciences
  • Maruani J; Département de Psychiatrie et D'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris F-75018, France; Université Paris Cité, NeuroDiderot, Inserm, FHU I2-D2, Paris F-75019, France; Centre ChronoS, GHU Paris, Psychiatry & Neurosciences
Psychiatry Res ; 334: 115811, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38442480
ABSTRACT
Currently, there is a major challenge in distinguishing between unipolar and bipolar major depressive episode. A significant body of research has been dedicated to identifying biomarkers that can aid in this differentiation due to its crucial implications, particularly for therapeutic and prognostic purposes. Among the biomarkers of interest, markers related to sleep and circadian rhythms show promise and could potentially aid in making this distinction. Nevertheless, no study has simultaneously examined sleep-wake disorders, circadian rhythms, and seasonal patterns using both subjective and objective measures. This study aims to characterize and compare the sleep-wake and rhythm disorders including patients with unipolar major depressive episode (n = 72) and with bipolar major depressive episode (n = 43) using both subjective markers (using self-report questionnaires and sleep complaints) and objective markers (using actigraphy). Patients with unipolar major depressive episode seem to experience significantly poorer quality of sleep, more symptoms of insomnia and lower sleep efficiency compared to patients with bipolar major depressive episode. On the other hand, patients with bipolar major depressive episode exhibit significantly more symptoms of motor retardation and hypersomnia compared to patients with unipolar disorder. These results hold significant implications for identifying individuals with unipolar major depressive episode or bipolar major depressive episode using sleep and circadian markers, and for developing recommended and personalized therapeutic strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Trastorno Depresivo Mayor Límite: Humans Idioma: En Revista: Psychiatry Res Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastorno Bipolar / Trastorno Depresivo Mayor Límite: Humans Idioma: En Revista: Psychiatry Res Año: 2024 Tipo del documento: Article Pais de publicación: Irlanda