Your browser doesn't support javascript.
loading
A Mammalian-Based Synthetic Biology Toolbox to Engineer Membrane-Membrane Interfaces.
Moghimianavval, Hossein; Mohapatra, Sonisilpa; Liu, Allen P.
Afiliación
  • Moghimianavval H; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Mohapatra S; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD, USA.
  • Liu AP; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA. allenliu@umich.edu.
Methods Mol Biol ; 2774: 43-58, 2024.
Article en En | MEDLINE | ID: mdl-38441757
ABSTRACT
Intercellular membrane-membrane interfaces are compartments with specialized functions and unique biophysical properties that are essential in numerous cellular processes including cell signaling, development, and immunity. Using synthetic biology to engineer or to create novel cellular functions in the intercellular regions has led to an increasing need for a platform that allows generation of functionalized intercellular membrane-membrane interfaces. Here, we present a synthetic biology platform to engineer functional membrane-membrane interfaces using a pair of dimerizing proteins in both cell-free and cellular environments. We envisage this platform to be a helpful tool for synthetic biologists who wish to engineer novel intercellular signaling and communication systems.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Biología Sintética Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Biología Sintética Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos