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Association between oxidative balance score and sarcopenia in older adults.
Mahmoodi, Marzieh; Shateri, Zainab; Nazari, Seyed Alireza; Nouri, Mehran; Nasimi, Nasrin; Sohrabi, Zahra; Dabbaghmanesh, Mohammad Hossein.
Afiliación
  • Mahmoodi M; Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shateri Z; Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Nazari SA; Department of Nutrition and Biochemistry, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
  • Nouri M; School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Nasimi N; Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. mehran_nouri71@yahoo.com.
  • Sohrabi Z; Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. mehran_nouri71@yahoo.com.
  • Dabbaghmanesh MH; Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Sci Rep ; 14(1): 5362, 2024 03 04.
Article en En | MEDLINE | ID: mdl-38438577
ABSTRACT
Sarcopenia is a progressive skeletal muscle disease in which oxidative stress has been proposed as one of the primary markers. The oxidative balance score (OBS) represents the oxidative balance of a person's dietary pattern using the merged intake of anti-oxidants and pro-oxidants. Therefore, the present study assessed the association between OBS and sarcopenia in Iranian older adults. In the current study, 80 people with sarcopenia and 80 without it were considered the case and control groups, respectively. All controls were matched by sex with cases. To confirm sarcopenia, skeletal muscle mass index (SMI), handgrip strength (HGS) measurement, and gait speed were used. Also, body composition was measured by bioelectrical impedance analysis (BIA). A valid and reliable food frequency questionnaire (FFQ) was used to assess all participants' dietary intake of pro-oxidants and anti-oxidants. Conditional logistic regression was applied to assess the association between OBS and sarcopenia. In the bivariate model, we observed lower odds of sarcopenia in the second and last tertile of OBS in comparison to the first tertile (T) (T2 - odds ratio (OR) = 0.414, 95% confidence interval (CI) 0.186-0.918 and T3 - OR = 0.101, 95% CI 0.041-0.248). After adjusting for potential confounders, the association was not significant in second and last tertile of OBS in comparision to the first one. The present study's findings demonstrated that overcoming exposure to anti-oxidants over pro-oxidants, as illustrated by a higher OBS, is not related to lower odds of sarcopenia in older adults.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcopenia / Antioxidantes Límite: Aged / Humans País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcopenia / Antioxidantes Límite: Aged / Humans País/Región como asunto: Asia Idioma: En Revista: Sci Rep Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido