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Stereotactic body radiation therapy for spinal metastases: A new standard of care.
Sacino, Amanda N; Chen, Hanbo; Sahgal, Arjun; Bettegowda, Chetan; Rhines, Laurence D; Maralani, Pejman; Redmond, Kristin J.
Afiliación
  • Sacino AN; Department of Neurosurgery, John Hopkins University, Baltimore, Maryland, USA.
  • Chen H; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
  • Sahgal A; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
  • Bettegowda C; Department of Neurosurgery, John Hopkins University, Baltimore, Maryland, USA.
  • Rhines LD; Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas, USA.
  • Maralani P; Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
  • Redmond KJ; Department of Radiation and Molecular Oncology, John Hopkins University, Baltimore, Maryland, USA.
Neuro Oncol ; 26(12 Suppl 2): S76-S87, 2024 03 04.
Article en En | MEDLINE | ID: mdl-38437670
ABSTRACT
Advancements in systemic therapies for patients with metastatic cancer have improved overall survival and, hence, the number of patients living with spinal metastases. As a result, the need for more versatile and personalized treatments for spinal metastases to optimize long-term pain and local control has become increasingly important. Stereotactic body radiation therapy (SBRT) has been developed to meet this need by providing precise and conformal delivery of ablative high-dose-per-fraction radiation in few fractions while minimizing risk of toxicity. Additionally, advances in minimally invasive surgical techniques have also greatly improved care for patients with epidural disease and/or unstable spines, which may then be combined with SBRT for durable local control. In this review, we highlight the indications and controversies of SBRT along with new surgical techniques for the treatment of spinal metastases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Radiocirugia Límite: Humans Idioma: En Revista: Neuro Oncol Asunto de la revista: NEOPLASIAS / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Columna Vertebral / Radiocirugia Límite: Humans Idioma: En Revista: Neuro Oncol Asunto de la revista: NEOPLASIAS / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido