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Two-year neurodevelopmental outcome in extremely preterm-born children: The Austrian Preterm Outcome Study Group.
Kiechl-Kohlendorfer, Ursula; Simma, Burkhard; Berger, Angelika; Urlesberger, Berndt; Wald, Martin; Haiden, Nadja; Fuiko, Renate; Ndayisaba, Jean-Pierre.
Afiliación
  • Kiechl-Kohlendorfer U; Department of Paediatrics II (Neonatology), Medical University Innsbruck, Innsbruck, Austria.
  • Simma B; Department of Paediatrics, Academic Teaching Hospital, Landeskrankenhaus Feldkirch, Feldkirch, Austria.
  • Berger A; Division of Neonatology, Paediatric Intensive Care and Neuropediatric, Department of Paediatrics and Adolescent Medicine, Comprehensive Centre for Paediatrics, Medical University of Vienna, Vienna, Austria.
  • Urlesberger B; Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Medical University Graz, Graz, Austria.
  • Wald M; Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Paracelsus Medical University Salzburg, Salzburg, Austria.
  • Haiden N; Department of Neonatology, Kepler University Hospital Linz, Linz, Austria.
  • Fuiko R; Division of Neonatology, Paediatric Intensive Care and Neuropediatric, Department of Paediatrics and Adolescent Medicine, Comprehensive Centre for Paediatrics, Medical University of Vienna, Vienna, Austria.
  • Ndayisaba JP; Department of Neurology, Medical University Innsbruck, Innsbruck, Austria.
Acta Paediatr ; 113(6): 1278-1287, 2024 06.
Article en En | MEDLINE | ID: mdl-38433292
ABSTRACT

AIM:

The current study determined the neurodevelopmental outcome of extremely preterm infants at 2 years of age.

METHODS:

All live-born infants 23-27 weeks of gestation born between 2011 and 2020 in Austria were included in a prospective registry. Neurodevelopmental outcome at 2 years of corrected age was assessed using Bayley Scales of Infant Development for both motor and cognitive scores, along with a neurological examination and an assessment of neurosensory function.

RESULTS:

2378 out of 2905 (81.9%) live-born infants survived to 2 years of corrected age. Follow-up data were available for 1488 children (62.6%). Overall, 43.0% had no, 35.0% mild and 22.0% moderate-to-severe impairment. The percentage of children with moderate-to-severe neurodevelopmental impairment decreased with increasing gestational age and was 31.4%, 30.5%, 23.3%, 19.0% and 16.5% at 23, 24, 25, 26 and 27 weeks gestational age (p < 0.001). Results did not change over the 10-year period. In multivariate analysis, neonatal complications as well as male sex were significantly associated with an increased risk of neurodevelopmental impairment.

CONCLUSION:

In this cohort study, a 22.0% rate of moderate-to-severe neurodevelopmental impairment was observed among children born extremely preterm. This national data is important for both counselling parents and guiding the allocation of health resources.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recien Nacido Extremadamente Prematuro / Trastornos del Neurodesarrollo Límite: Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Acta Paediatr Año: 2024 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Noruega
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recien Nacido Extremadamente Prematuro / Trastornos del Neurodesarrollo Límite: Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Europa Idioma: En Revista: Acta Paediatr Año: 2024 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Noruega