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Supermicrosurgery lymphaticovenous and lymphaticolymphatic anastomosis: Technical detail and short-term follow-up for immediate lymphatic reconstruction in breast cancer treatment-related lymphedema prevention.
Brahma, Bayu; Yamamoto, Takumi; Panigoro, Sonar Soni; Haryono, Samuel Johny; Yusuf, Prasandhya Astagiri; Priambodo, Purnomo Sidi; Harimurti, Kuntjoro; Taher, Akmal.
Afiliación
  • Brahma B; Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgical Oncology, Dharmais Cancer Hospital-National Cancer Center, Jakarta, Indonesia.
  • Yamamoto T; Department of Plastic and Reconstructive Surgery, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: tyamamoto-tky@umin.ac.jp.
  • Panigoro SS; Oncology Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
  • Haryono SJ; Department of Surgical Oncology, Dharmais Cancer Hospital-National Cancer Center, Jakarta, Indonesia.
  • Yusuf PA; Department of Medical Physiology and Biophysics/Medical Technology IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • Priambodo PS; Department of Electrical Engineering, Faculty of Engineering, Universitas Indonesia, Jakarta, Indonesia.
  • Harimurti K; Division of Geriatrics/Clinical Epidemiological Unit, Department of Internal Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
  • Taher A; Department of Urology, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
J Vasc Surg Venous Lymphat Disord ; 12(4): 101863, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38428499
ABSTRACT

OBJECTIVE:

We describe the feasibility and short-term outcome of our surgical technique to repair the lymph vessel disruption directly after axillary lymph node dissection during breast cancer surgery. This procedure is called immediate lymphatic reconstruction to prevent breast cancer treatment-related lymphedema (BCRL), which frequently occurs after axillary lymph node dissection. The surgical technique consisted of lymphaticovenous anastomosis (LVA) or lymphaticolymphatic anastomosis. We named the procedure lymphatic bypass supermicrosurgery (LBS).

METHODS:

This study used a retrospective cohort design of patients with breast cancer between May 2020 and February 2023. LBS was performed by making an intima-to-intima coaptation between afferent lymph vessels and the recipient's veins (LVA) or efferent lymph vessels lymphaticolymphatic anastomosis.

RESULTS:

A total of 82 patients underwent lymphatic bypass. The mean age of patients was 50 ± 12 years, and most had stage III breast cancer (n = 59 [72%]). LVA was the most common type of lymphatic bypass (94.6%). The median number of LVA was 1 (range, 1-4) and 1 (range, 1-3) for lymphaticolymphatic anastomosis. The median follow-up time was 12.5 months (range, 1-33 months). The 50 patients who had postoperative indocyanine green lymphography described arm dermal backflow stage 0 in 20 (40%), stage 1 in 19 (38%), stage 2 in 2 (4%), and stage 3 in 9 (18%) cases. The proportion of BCRL was 11 (22%), and subclinical lymphedema was 19 (38%) in this period. Most cases were in stable subclinical lymphedema (10, 58.8%). The 1-year and 2-year BCRL rates were 14% (95% confidence interval, 4%-23.9%) and 22% (95% confidence interval, 10.1%-33.9%), respectively.

CONCLUSIONS:

Along with the emerging immediate lymphatic reconstruction, LBS is a feasible supermicrosurgery technique that may have a potential role in BCRL prevention. A randomized controlled study would confirm the effectiveness of the technique.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Anastomosis Quirúrgica / Estudios de Factibilidad / Vasos Linfáticos / Linfedema del Cáncer de Mama / Escisión del Ganglio Linfático / Microcirugia Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: J Vasc Surg Venous Lymphat Disord Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Anastomosis Quirúrgica / Estudios de Factibilidad / Vasos Linfáticos / Linfedema del Cáncer de Mama / Escisión del Ganglio Linfático / Microcirugia Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: J Vasc Surg Venous Lymphat Disord Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Estados Unidos