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The Impact of Hypoglossal Nerve Stimulation on Secondary Health Outcomes.
Freeman, Cecilia G; Durgham, Ryan; Ren, Emily; Conti, Keith R; Yeakel, Heather; Fan, Timothy; Brown, David M; Ohlstein, Jason F; Keeler, Jarrod A.
Afiliación
  • Freeman CG; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
  • Durgham R; Temple/St. Luke's School of Medicine, Bethlehem, PA, USA.
  • Ren E; Temple/St. Luke's School of Medicine, Bethlehem, PA, USA.
  • Conti KR; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
  • Yeakel H; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
  • Fan T; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
  • Brown DM; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
  • Ohlstein JF; Specialty Physician Associates, Bethlehem, PA, USA.
  • Keeler JA; Department of Otolaryngology-Head and Neck Surgery, St. Luke's University Health Network, Bethlehem, PA, USA.
Ear Nose Throat J ; : 1455613241235538, 2024 Feb 29.
Article en En | MEDLINE | ID: mdl-38424691
ABSTRACT

Objectives:

Obstructive sleep apnea (OSA) is a prevalent sleep disorder that can increase the risk of hypertension, diabetes, obesity, and cardiovascular diseases. Hypoglossal nerve stimulation (HGNS) is an alternative therapy for OSA in patients who cannot tolerate continuous positive airway pressure. Understanding the impact of HGNS on blood pressure, hemoglobin A1C (A1C), and body mass index (BMI) currently remains limited.

Methods:

A retrospective review study of HGNS outcomes at a single practice from January 2020 to November 2022 was conducted. Inclusion/exclusion criteria were based on HGNS eligibility and postoperative titration study. Statistical analysis and data management were performed using statistical software, R (v.4.2.1; R Core Team). Paired Student's T test, Fisher's exact test, and McNemar's exact test were utilized for statistical analysis. P values less than .05 were considered statistically significant.

Results:

Sixty-three patients were included in this study. A significant decrease in mean apnea-hypopnea index was noted following HGNS (mean change -28; P < .0001). Similar significant decreases were also seen in mean arterial pressures (mean change -8.4, P < .0001). There was a significant change in overall antihypertensive medication requirements and in requirements ≥3 medications (P < .0005, P = .03). There was a trend toward reduction in A1C; however, there was no change in BMI or number of diabetes medications taken.

Conclusions:

Our results reinforce previous findings that HGNS is an effective treatment option for carefully selected patients with OSA. In addition, our findings suggest that HGNS may improve patients' quality of life while minimizing OSA associated morbidity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ear Nose Throat J Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Ear Nose Throat J Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos