Peroxisome-based metabolic engineering for biomanufacturing and agriculture.
Trends Biotechnol
; 42(9): 1161-1176, 2024 Sep.
Article
en En
| MEDLINE
| ID: mdl-38423802
ABSTRACT
Subcellular compartmentalization of metabolic pathways plays a crucial role in metabolic engineering. The peroxisome has emerged as a highly valuable and promising compartment for organelle engineering, particularly in the fields of biological manufacturing and agriculture. In this review, we summarize the remarkable achievements in peroxisome engineering in yeast, the industrially popular biomanufacturing chassis host, to produce various biocompounds. We also review progress in plant peroxisome engineering, a field that has already exhibited high potential in both biomanufacturing and agriculture. Moreover, we outline various experimentally validated strategies to improve the efficiency of engineered pathways in peroxisomes, as well as prospects of peroxisome engineering.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peroxisomas
/
Agricultura
/
Ingeniería Metabólica
Idioma:
En
Revista:
Trends Biotechnol
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido