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Pyoderma Gangrenosum: Diagnostic Criteria, Subtypes, Systemic Associations, and Workup.
Zaino, Mallory L; Schadt, Courtney R; Callen, Jeffrey P; Owen, Lafayette G.
Afiliación
  • Zaino ML; Department of Dermatology, University of Louisville, 3810 Springhurst Boulevard, Suite 200, Louisville, KY, USA. Electronic address: mlzain01@louisville.edu.
  • Schadt CR; Department of Dermatology, University of Louisville, 3810 Springhurst Boulevard, Suite 200, Louisville, KY, USA.
  • Callen JP; Department of Dermatology, University of Louisville, 3810 Springhurst Boulevard, Suite 200, Louisville, KY, USA.
  • Owen LG; Department of Dermatology, University of Louisville, 3810 Springhurst Boulevard, Suite 200, Louisville, KY, USA.
Dermatol Clin ; 42(2): 157-170, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38423678
ABSTRACT
Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis with variable clinical features. The classic presentation is an ulceration with an erythematous to violaceous undermined border. Extracutaneous manifestations may occur. Associated systemic diseases include inflammatory bowel disease, inflammatory arthritides, and hematologic disorders. The pathophysiologic mechanism of disease is not completely known but likely related to the cumulative impact of inflammation, immune-mediated neutrophilic dysfunction, and genetic predisposition. Incidence is between 3 and 10 people per million but may be greater due to under recognition. In this article, we will discuss the diagnostic criteria, disease subtypes, systemic associations, and workup.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Piodermia Gangrenosa Límite: Humans Idioma: En Revista: Dermatol Clin Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Piodermia Gangrenosa Límite: Humans Idioma: En Revista: Dermatol Clin Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos