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Patterned Au@Ag nanoarrays with electrically stimulated laccase-mimicking activity for dual-mode detection of epinephrine.
Cui, Anni; Zhang, Jialu; Liu, Zhifei; Mu, Xin; Zhong, Xiahua; Xu, Haitao; Shan, Guiye.
Afiliación
  • Cui A; Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun, 130024, China.
  • Zhang J; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130041, China.
  • Liu Z; High School Attached to Northeast Normal University International Division, Changchun, 130021, China.
  • Mu X; Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun, 130024, China.
  • Zhong X; Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun, 130024, China.
  • Xu H; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, 130041, China. Electronic address: xvhaitao9290@126.com.
  • Shan G; Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun, 130024, China. Electronic address: shangy229@nenu.edu.cn.
Talanta ; 272: 125821, 2024 May 15.
Article en En | MEDLINE | ID: mdl-38412753
ABSTRACT
Epinephrine (EP) is a crucial neurotransmitter in the central nervous system. However, an abnormal level of EP in biological fluids can lead to various diseases. Therefore, it is essential to rapidly and accurately detect EP content. Herein, electrically stimulated patterned Au@Ag nanoarrays with laccase-mimicking activity were designed for the dual-mode detection of EP concentration. The patterned Au@Ag nanoarrays exhibit excellent electrochemical properties and electrically stimulated laccase-mimicking activity. They provide sensitive electrochemical responses for detecting EP content. Simultaneously, the Au@Ag nanoarrays can catalyze the oxidation of EP, enabling its detection through a colorimetric process. This dual-mode approach achieves the detection of EP content over a wide linear range of 0.5-200 µM, with a low detection limit of 0.152 µM. Furthermore, the utility of these nanoarrays for sensing EP in human serum was evaluated. This work provides a convenient method using patterned nanozyme array for the visible, rapid and accurate detection of EP content. It provides the important implication for the development of portable and reliable on-site analytical instruments.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lacasa / Oro Límite: Humans Idioma: En Revista: Talanta Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lacasa / Oro Límite: Humans Idioma: En Revista: Talanta Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos